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79470

D(+)-2-Phosphoglyceric acid sodium salt hydrate

≥75% (calc. on dry substance, enzymatic)

Synonym(s):

D-Glycerate 2-phosphate sodium salt, Sodium D-2-phosphoglycerate hydrate

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About This Item

Empirical Formula (Hill Notation):
C3H7O7P · xNa+ · yH2O
CAS Number:
83418-48-8
Molecular Weight:
186.06 (anhydrous free acid basis)
UNSPSC Code:
12352204
PubChem Substance ID:
329768458
NACRES:
NA.26
Assay:
≥75% (calc. on dry substance, enzymatic)
Form:
powder

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InChI key

PXJAQZYAJDMQJH-YBBRRFGFSA-N

SMILES string

O=C(O)[C@@H](CO)OP(O)(O)=O.C.C

assay

≥75% (calc. on dry substance, enzymatic)

form

powder

impurities

≤1% Pi, ≤35% water

storage temp.

−20°C

Quality Level

100

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1 of 4

This Item
197106178661668
D(+)-2-Phosphoglyceric acid sodium salt hydrate ≥75% (calc. on dry substance, enzymatic)

Sigma-Aldrich

79470

D(+)-2-Phosphoglyceric acid sodium salt hydrate

L-2-Phosphoglyceric acid disodium salt hydrate ≥80% (CE)

Sigma-Aldrich

19710

L-2-Phosphoglyceric acid disodium salt hydrate

D-Glyceric acid sodium salt ≥95.0% (TLC)

Sigma-Aldrich

61786

D-Glyceric acid sodium salt

rac-Glycerol 1-phosphate sodium salt hydrate ≥95.0% (TLC)

Sigma-Aldrich

61668

rac-Glycerol 1-phosphate sodium salt hydrate

form

powder

form

solid

form

powder or crystals

form

powder or solid

assay

≥75% (calc. on dry substance, enzymatic)

assay

≥80% (CE)

assay

≥95.0% (TLC)

assay

≥95.0% (TLC), 95-102% anhydrous basis (corrected for sodium, T)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

impurities

≤1% Pi, ≤35% water

impurities

≤0.2% P(i), ≤35% water

impurities

-

impurities

≤35% water

storage temp.

−20°C

storage temp.

−20°C

storage temp.

-

storage temp.

2-8°C

Biochem/physiol Actions

Enantiomerically pure metabolite of glycolysis/gluconeogenesis and also substrate for a number of important enzymes in central metabolism like enolase and phosphoglycerate mutase.
The enzyme enolase is responsible for reversible conversion of 2-phosphoglycerate (2-PG) into phosphoenolpyruvate (PEP). Phosphoglycerate mutase causes reversible isomerization of 3-phosphoglycerate and 2-phosphoglycerate in glycolysis and gluconeogenesis.[1][2]

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
0000539706
0000539706
0000509933
0000509933
0000483145

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T M Larsen et al.
Biochemistry, 35(14), 4349-4358 (1996-04-09)
The equilibrium mixture of yeast enolase with substrate, 2-phospho-D-glycerate (2-PGA), and product, phosphoenolpyruvate (P-enolpyruvate), has been crystallized from solutions of poly(ethylene glycol) (PEG) at pH 8.0. Crystals belong to the space group C2 and have unit cell dimensions a =
Shivangi Agarwal et al.
Biochimica et biophysica acta, 1784(7-8), 986-994 (2008-05-06)
alpha-enolase of Bacillus anthracis has recently been classified as an immunodominant antigen and a potent virulence factor determinant. alpha-enolase (2-phospho-d-glycerate hydrolase (EC 4.2.1.11), a key glycolytic metalloenzyme catalyzes the dehydration of d-(+)-2-phosphoglyceric acid to phosphoenolpyruvate. Interaction of surface bound alpha-enolase
E Zhang et al.
Biochemistry, 36(41), 12526-12534 (1997-11-05)
Enolase, a glycolytic enzyme that catalyzes the dehydration of 2-phospho-d-glycerate (PGA) to form phosphoenolpyruvate (PEP), is a homodimer in all eukaryotes and many prokaryotes. Here, we report the crystal structure of a complex between yeast enolase and an equilibrium mixture
Molecular characterization of phosphoglycerate mutase in archaea.
van der Oost J, et al.
FEMS Microbiology Letters, 212, 111-120 (2002)
Jin-Ha Lee et al.
FEMS microbiology letters, 259(2), 240-248 (2006-06-01)
Enolase on the surface of streptococci putatively facilitates pathogenic invasion of the host organisms. The related Leuconostoc mesenteroides 512FMCM is nonpathogenic, but it too has an extracellular enolase. Purified isolates of extracellular dextransucrase from cultures of L. mesenteroides contain minute
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