All Photos(1)

80666

Sigma-Aldrich

Hexarelin

≥90% (HPLC)

Synonym(s):
HEX, Examorelin, L-Histidyl-2-methyl-D-tryptophyl-L-alanyl-L-tryptophyl-D-phenylalanyl-L-lysinamide
Empirical Formula (Hill Notation):
C47H58N12O6
CAS Number:
Molecular Weight:
887.04
PubChem Substance ID:
NACRES:
NA.26

Quality Level

assay

≥90% (HPLC)

form

powder

color

white

solubility

H2O: 1 mg/mL, clear, colorless

storage temp.

−20°C

SMILES string

C[C@H](NC(=O)[C@@H](Cc1c(C)[nH]c2ccccc12)NC(=O)[C@@H](N)Cc3cnc[nH]3)C(=O)N[C@@H](Cc4c[nH]c5ccccc45)C(=O)N[C@H](Cc6ccccc6)C(=O)N[C@@H](CCCCN)C(N)=O

InChI

1S/C47H58N12O6/c1-27-34(33-15-7-9-17-37(33)54-27)23-41(58-44(62)35(49)22-31-25-51-26-53-31)45(63)55-28(2)43(61)57-40(21-30-24-52-36-16-8-6-14-32(30)36)47(65)59-39(20-29-12-4-3-5-13-29)46(64)56-38(42(50)60)18-10-11-19-48/h3-9,12-17,24-26,28,35,38-41,52,54H,10-11,18-23,48-49H2,1-2H3,(H2,50,60)(H,51,53)(H,55,63)(H,56,64)(H,57,61)(H,58,62)(H,59,65)/t28-,35-,38-,39+,40-,41+/m0/s1

InChI key

RVWNMGKSNGWLOL-GIIHNPQRSA-N

Related Categories

Biochem/physiol Actions

Hexarelin (HEX), a ghrelin analogue, is a growth hormone secretagogue receptor agonist, a growth hormone releasing peptide. Hexarelin may be used as an internal standard in quantitative analysis (via chromatography etc.) of prohibited growth hormone enhancing drugs such as GHRP-2. The potential use of Hexarelin as a therapeutic has prompted research studies on its physiological effects in vitro and in vivo.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class Code

13 - Non Combustible Solids

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

Olivier Humbert et al.
Science translational medicine, 11(503) (2019-08-02)
Reactivation of fetal hemoglobin (HbF) is being pursued as a treatment strategy for hemoglobinopathies. Here, we evaluated the therapeutic potential of hematopoietic stem and progenitor cells (HSPCs) edited with the CRISPR-Cas9 nuclease platform to recapitulate naturally occurring mutations identified in...
Erin M Euliano et al.
Scientific reports, 9(1), 11372-11372 (2019-08-08)
Reverse transcription polymerase chain reaction (RT-PCR) is the gold standard for the molecular diagnosis of many infectious diseases, including RNA viruses, but is generally limited to settings with access to trained personnel and laboratory resources. We have previously reported a...
Rosalyn Gloag et al.
Nature ecology & evolution, 1(1), 11-11 (2017-08-16)
Some invasive hymenopteran social insects found new populations with very few reproductive individuals. This is despite the high cost of founder effects for such insects, which generally require heterozygosity at a single locus-the complementary sex determiner, csd-to develop as females....
Yujiro Hayashi et al.
Frontiers in oncology, 10, 755-755 (2020-06-09)
Recent studies showed the clinical utility of next-generation sequencing of urinary cell-free DNA (cfDNA) from patients with urothelial bladder cancer (UBC). In this study, we aimed to develop urinary cfDNA analysis by droplet digital PCR (ddPCR) as a high-throughput and...
Yujiro Hayashi et al.
Molecular oncology, 14(10), 2375-2383 (2020-06-14)
Telomerase reverse transcriptase (TERT) promoter mutations are frequently found in tumors or urine from patients with urothelial carcinoma (UC). TERT promoter mutations are also detected in urine from patients with no evidence of cancer but are associated with subsequent UC...

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