81838

L-C-Propargylglycine

≥99.0% (TLC)

• Synonym(s): L-Propargylglycine, (S)-2-Amino-4-pentynoic acid
• Empirical Formula (Hill Notation): C₅H₇NO₂
• CAS Number: 23235-01-0
• Molecular Weight: 113.11
• Beilstein/REAXYS Number: 2347861
• MDL number: MFCD00077855
• UNSPSC Code: 12352209
• eCl@ss: 32160406
• PubChem Substance ID: 57652892
• NACRES: NA.26

Properties

• Product Name: L-C-Propargylglycine, ≥99.0% (TLC)
• Quality Level: 100
• assay: ≥99.0% (TLC)
• form: powder
• color: white
• mp: 235-239 °C
• application(s): peptide synthesis
• storage temp.: 2-8°C
• SMILES string: N[C@@H](CC#C)C(O)=O
• InChI: 1S/C5H7NO2/c1-2-3-4(6)5(7)8/h1,4H,3,6H2,(H,7,8)/t4-/m0/s1
• InChI key: DGYHPLMPMRKMPD-BYPYZUCNSA-N

Description

Application

Reagent for the irreversible inactivation of γ-cystathionase[1][2]; affinity labeling reagent for γ-cystathionase and other enzymes[3]; peptides containing this amino acid can be tritiated to high specific radioactivity[4]

Biochem/physiol Actions

L-C-Propargylglycine, a specific inhibitor of H(2)S synthase of cystathionine-γ-lyase (CSE), may be used to study the role of H2S in regulation of biological processes.

L-propargylglycine (PAG), an inhibitor of cystathionine γ-lyase (CSE), is useful in studies of hydrogen sulphide synthesis and bioactivity.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)