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83266

Sigma-Aldrich

Magnesium sulfate solution

BioUltra, for molecular biology

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Synonym(s):
Magnesium Sulphate, Magnesium(II) sulfate, MgSO4
Empirical Formula (Hill Notation):
MgSO4
CAS Number:
Molecular Weight:
120.37
MDL number:
UNSPSC Code:
12161700
PubChem Substance ID:
NACRES:
NA.25

grade

for molecular biology

Quality Level

product line

BioUltra

form

liquid

concentration

2.5 M in H2O

impurities

DNases, none detected
RNases, none detected
insoluble matter, passes filter test
phosphatases, none detected
proteases, none detected
<0.002% total nitrogen (N)

pH

6.5-8.5 (25 °C)

anion traces

chloride (Cl-): ≤5 mg/kg

cation traces

Al: ≤1 mg/kg
As: ≤0.1 mg/kg
Ba: ≤1 mg/kg
Bi: ≤1 mg/kg
Ca: ≤20 mg/kg
Cd: ≤1 mg/kg
Co: ≤1 mg/kg
Cr: ≤1 mg/kg
Cu: ≤1 mg/kg
Fe: ≤1 mg/kg
K: ≤20 mg/kg
Li: ≤1 mg/kg
Mn: ≤1 mg/kg
Mo: ≤1 mg/kg
Na: ≤20 mg/kg
Ni: ≤1 mg/kg
Pb: ≤1 mg/kg
Sr: ≤1 mg/kg
Zn: ≤1 mg/kg

λ

neat

UV absorption

λ: 260 nm Amax: 0.03
λ: 280 nm Amax: 0.02

SMILES string

[Mg++].[O-]S([O-])(=O)=O

InChI

1S/Mg.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2

InChI key

CSNNHWWHGAXBCP-UHFFFAOYSA-L

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Application


  • Optimization in vinasse processing: Magnesium sulfate plays a role in optimizing the electrodialysis and nanofiltration process of vinasse, enhancing environmental sustainability and efficiency in waste management practices, which are crucial for industrial applications including the production of IVD reagents (Duarte et al., 2023).

  • Screening of flame retardant residues: In analytical methodologies like QuEChERS-gas chromatography, magnesium sulfate is employed for its efficacy in the extraction and cleanup steps, underscoring its importance in ensuring high-purity standards required for accurate and reliable diagnostic assays (Li et al., 2023).

Biochem/physiol Actions

Magnesium sulphate can be used to treat acute severe asthma. It is mainly considered as a neuroprotective agent.

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Cardiovascular Disease
Handbook on the Toxicology of Metals, 801, 313-331 (2015)
Effects of nebulised magnesium sulphate on inflammation and function of the guinea-pig airway
Turner DL, et al.
European Journal of Pharmacology, 801, 79-85 (2017)
Lex W Doyle et al.
Obstetrics and gynecology, 113(6), 1327-1333 (2009-05-23)
To systematically review rates of neurologic outcomes reported in childhood for the preterm fetus exposed to antenatal magnesium sulfate. We searched the Cochrane Pregnancy and Childbirth Group's Trials Register, CENTRAL (The Cochrane Library 2008, Issue 3), relevant references from retrieved
Lex W Doyle
Current opinion in pediatrics, 24(2), 154-159 (2012-01-10)
Antenatal magnesium sulfate may reduce the excessive rates of cerebral palsy in survivors of very preterm birth. There are five randomized controlled trials of magnesium sulfate therapy given to the mother prior to very preterm birth which have reported neurological
Robert J Floor et al.
Chembiochem : a European journal of chemical biology, 15(11), 1660-1672 (2014-07-01)
We explored the use of a computational design framework for the stabilization of the haloalkane dehalogenase LinB. Energy calculations, disulfide bond design, molecular dynamics simulations, and rational inspection of mutant structures predicted many stabilizing mutations. Screening of these in small

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