86524

Sigma-Aldrich

CM-Dextran sodium salt

BioXtra

Synonym(s):
CM-D, Carboxymethyl-dextran sodium salt
CAS Number:
MDL number:
NACRES:
NA.25
Pricing and availability is not currently available.

Quality Level

product line

BioXtra

impurities

≤10% water

solubility

H2O: 10 mg/mL, clear, colorless

anion traces

chloride (Cl-): ≤3500 mg/kg
sulfate (SO42-): ≤200 mg/kg

cation traces

Ca: ≤500 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤10 mg/kg
K: ≤500 mg/kg
Mg: ≤100 mg/kg
Mn: ≤5 mg/kg
Ni: ≤5 mg/kg
Pb: ≤10 mg/kg
Zn: ≤10 mg/kg

λ

10 mg/mL in H2O

UV absorption

λ: 260 nm Amax: ≤0.03
λ: 280 nm Amax: ≤0.04

Application

Carboxymethyl-dextran (CMD) may be used as a matrix component to prepare surfaces for cell adherence and culture and in the construction of polymer membranes used in the development of biomaterials/biostructures for applications such as drug delivery.

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis
Certificate of Origin
  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  4. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  5. What is the molecular weight of Product No. 86524, CM-Dextran sodium salt?

    According to our supplier, the molecular weight is 10000 - 20000 Daltons.

  6. What is the carboxyl content of Product No. 86524, CM-Dextran sodium salt?

    The carboxyl content is within the limits 1.1-1.5 mmol carboxyl/g.

  7. What is the difference between product 86524, CM-Dextran sodium salt and the discontinued product 27560?

    The two products are comparable.  They are chemically the same substance with similar testing specifications.

  8. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

  9. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

Carina Kuehn et al.
Acta biomaterialia, 8(2), 619-626 (2011-11-17)
Rat insulinoma cells (INS-1), an immortalized pancreatic beta cell line, were cultured on low-fouling carboxymethyl-dextran (CMD) layers bearing fibronectin, the tripeptide Arg-Gly-Asp (RGD) or CDPGYIGSR, a laminin nonapeptide. INS-1 cells were non-adherent on CMD and RGE but adhered to fibronectin-...
in vitromorphogenesis of PANC-1 cells into islet-like aggregates using RGD-covered dextran derivative surfaces.
Dubiel EA, Kuehn C, Wang R, Vermette P.
Colloids and Surfaces, B: Biointerfaces, 89, 117-125 (2012)
Characterization of Chitosan-Carboxymethyl Dextran Nanoparticles as a Drug Carrier and as a Stimulator of Mouse Splenocytes.
Lin YS, Radzi R, Morimoto M, et al.
Journal of Biomaterials Science. Polymer Edition, doi: 10-doi: 10 (2011)
Afanasy V Lunin et al.
Journal of colloid and interface science, 541, 143-149 (2019-01-28)
Exploration of novel types of iron oxide nanoparticles as well as novel versatile ways to prepare them in a controlled manner keeping in mind necessity of narrow size distributions and high colloidal and chemical stability is an important task for...
Wang Xiao et al.
The journal of physical chemistry. B, 115(46), 13796-13802 (2011-10-25)
In this study, photoswitchable microcapsules were fabricated based on host-guest interactions between α-cyclodextrin (α-CD) and azobenzene (Azo). Carboxymethyl dextran-graft-α-CD (CMD-g-α-CD) and poly(acrylic acid) N-aminododecane p-azobenzeneaminosuccinic acid (PAA-C(12)-Azo) were assembled layer by layer on CaCO(3) particles. α-CD-rhodamine B (α-CD-RhB), used as...
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