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86614

Sigma-Aldrich

Tetraethylammonium chloride

BioUltra, for molecular biology, ≥99.0% (AT)

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Synonym(s):
Etamon chloride, TEAC, TEA chloride
Linear Formula:
(C2H5)4N(Cl)
CAS Number:
Molecular Weight:
165.70
Beilstein:
3563247
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.26

grade

for molecular biology

Quality Level

product line

BioUltra

Assay

≥99.0% (AT)

form

powder

mol wt

165.70 g/mol

technique(s)

gas chromatography (GC): suitable

impurities

DNases, none detected
RNases, none detected
insoluble matter, passes filter test
phosphatases, none detected
proteases, none detected

solubility

H2O: 1 M at 20 °C, clear, colorless

anion traces

bromide (Br-): ≤500 mg/kg
sulfate (SO42-): ≤50 mg/kg

cation traces

Al: ≤5 mg/kg
As: ≤0.1 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
Na: ≤50 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

λ

1 M in H2O

UV absorption

λ: 260 nm Amax: 0.03
λ: 280 nm Amax: 0.03

SMILES string

[Cl-].CC[N+](CC)(CC)CC

InChI

1S/C8H20N.ClH/c1-5-9(6-2,7-3)8-4;/h5-8H2,1-4H3;1H/q+1;/p-1

InChI key

YMBCJWGVCUEGHA-UHFFFAOYSA-M

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This Item
T226587718T19526
Tetraethylammonium chloride BioUltra, for molecular biology, ≥99.0% (AT)

Sigma-Aldrich

86614

Tetraethylammonium chloride

Premium Grade
Tetramethylammonium chloride BioUltra, for molecular biology, ≥99.0% (AT)

Sigma-Aldrich

87718

Tetramethylammonium chloride

Premium Grade
product line

BioUltra

product line

-

product line

BioUltra

product line

-

assay

≥99.0% (AT)

assay

≥98% (titration)

assay

≥99.0% (AT)

assay

≥98%

form

powder

form

powder

form

crystals

form

-

mol wt

165.70 g/mol

mol wt

-

mol wt

-

mol wt

-

technique(s)

gas chromatography (GC): suitable

technique(s)

blocking: suitable

technique(s)

-

technique(s)

-

General description

Tetraethylammonium (TEA), a simple quaternary ammonium compound, is commonly used to block potassium channels. It can physically enter the pore and block the channel. Additionally, TEA either imitates or antagonizes the actions of choline and acetylcholine, two other quaternary ammonium ions.

Application

Tetraethylammonium chloride has been used:

  • as a pharmacological agent in electrophysiology to study its pharmacological effects on Cnidarians
  • as a component in refolding buffer for protein refolding
  • to puff onto isolated patches to block voltage-gated K+ (Kv3) channels and post-hoc evaluation

Features and Benefits

  • Assay: ≥99.0% (AT), BioUltra, for molecular biology
  • Suitable for gas chromatography (GC)

Other Notes

TEACl method of DNA-DNA hybridization

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

201.2 °F - closed cup

Flash Point(C)

94 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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