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87809

Retinyl propionate

≥98.0% (sum of isomers, HPLC), ~2500 U/mg

Synonym(s):

Vitamin A propionate

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$331.00

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About This Item

Empirical Formula (Hill Notation):
C23H34O2
CAS Number:
7069-42-3
Molecular Weight:
342.51
NACRES:
NA.79
PubChem Substance ID:
57653182
eCl@ss:
34058020
UNSPSC Code:
12352205
EC Number:
230-363-2
MDL number:
MFCD00129785
Beilstein/REAXYS Number:
2475675

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Product Name

Retinyl propionate, ≥98.0% (sum of isomers, HPLC), ~2500 U/mg

InChI key

SFRPDSKECHTFQA-ONOWFSFQSA-N

InChI

1S/C23H34O2/c1-7-22(24)25-17-15-19(3)11-8-10-18(2)13-14-21-20(4)12-9-16-23(21,5)6/h8,10-11,13-15H,7,9,12,16-17H2,1-6H3/b11-8+,14-13+,18-10+,19-15+

SMILES string

CCC(=O)OC\C=C(C)\C=C\C=C(C)\C=C\C1=C(C)CCCC1(C)C

biological source

synthetic

assay

≥98.0% (sum of isomers, HPLC)

form

liquid

specific activity

~2500 U/mg

contains

BHT as stabilizer

impurities

~5% cis-isomers

color

green-yellow to very dark green-yellow
 yellow to very dark yellow

storage temp.

2-8°C

Quality Level

100

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This Item
R3375R325017772
Retinyl propionate ≥98.0% (sum of isomers, HPLC), ~2500 U/mg

Sigma-Aldrich

87809

Retinyl propionate

Retinyl palmitate Type IV, ~1,800,000 USP units/g, oil

Sigma-Aldrich

R3375

Retinyl palmitate

Retinyl acetate synthetic, matrix dispersion, 475,000-650,000 USP units/g

Sigma-Aldrich

R3250

Retinyl acetate

Retinol ≥95.0% (HPLC), ~2700 U/mg

Sigma-Aldrich

17772

Retinol

assay

≥98.0% (sum of isomers, HPLC)

assay

≥90% (HPLC)

assay

-

assay

≥95.0% (HPLC)

biological source

synthetic

biological source

synthetic (organic)

biological source

synthetic

biological source

synthetic

form

liquid

form

oil

form

matrix dispersion

form

(Powder or Crystal with Lumps)

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

−20°C

Quality Level

100

Quality Level

100

Quality Level

200

Quality Level

100

color

green-yellow to very dark green-yellow, yellow to very dark yellow

color

yellow to orange

color

yellow

color

yellow to dark yellow

Application

Retinyl propionate has been used to determine its effects on performance, egg quality, serum and egg oxidative status and vitamin A levels in laying quails.[1]

Biochem/physiol Actions

Retinyl esters provide pools of vitamin A that are converted into retinol and other retinoids as needed. Retinyl propionate is used in various formulations to control wrinkles.[2]

General description

Retinal, retinol and retinoic acid are the aldehyde, alcohol and acid forms of vitamin A. The retinoids exist as many geometric isomers due to the unsaturated bonds in the aliphatic chain. Retinoids also exist as retinyl esters such as retinyl propionate, retinyl acetate and retinyl palmitate.

Other Notes

1 international unit according to PH EUR II, 217 (1983)

pictograms

Health hazard
GHS08

signalword

Danger

hcodes

H360,H413

Hazard Classifications

Aquatic Chronic 4 - Repr. 1B

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 2

flash_point_f

262.4 °F - closed cup

flash_point_c

128 °C - closed cup

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

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Certificates of Analysis (COA)

Lot/Batch Number
BCCL3815
BCCL3548
BCCJ0721
BCCC8595
BCBS0903V

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Retinyl propionate and climbazole combination demonstrates clinical improvement to the appearance of hyperpigmentation and deep wrinkling with minimal irritation
Hawkins S, et al.
International Journal of Cosmetic Science, 39(6), 589-599 (2017)
J J J Fu et al.
The British journal of dermatology, 162(3), 647-654 (2010-04-09)
Tretinoin is considered the benchmark prescription topical therapy for improving fine facial wrinkles, but skin tolerance issues can affect patient compliance. In contrast, cosmetic antiwrinkle products are well tolerated but are generally presumed to be less efficacious than tretinoin. To
Effect of retinol and retinol esters on performance, egg quality, and blood and egg vitamin A levels in laying quails
Ilhan M and BULBUL T
Turkish Journal of Veterinary and Animal Sciences, 40(5), 590-597 (2016)
C Green et al.
Clinical and experimental dermatology, 23(4), 162-167 (1999-01-23)
The clinical and histological effects of retinyl propionate cream (a retinyl ester) on extrinsic skin ageing (photo-ageing) in man were assessed in a double-blind randomized placebo-controlled study of 80 subjects, individual parameters of this being assessed for each treatment site
S Donoghue et al.
The Journal of nutrition, 115(12), 1562-1571 (1985-12-01)
Twelve ewes were fed retinyl propionate equivalent to 12,000 micrograms retinol/kg body weight per day for the last two trimesters of pregnancy (group fed high vitamin A). Four ewes received a control level of 120 micrograms/kg body weight per day.
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