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87918

Sigma-Aldrich

Tetramethylrhodamine isothiocyanate mixed isomers

suitable for fluorescence, mixture of isomers

Synonym(s):
MRITC, TRITC, Tetramethylrhodamine B isothiocyanate
Empirical Formula (Hill Notation):
C25H21N3O3S
CAS Number:
Molecular Weight:
443.52
NACRES:
NA.32

Quality Level

form

powder

solubility

DMSO: soluble
methanol: soluble

fluorescence

λex 529 nm; λem 596 nm in DMSO

suitability

suitable for fluorescence

storage temp.

2-8°C

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General description

Tetramethylrhodamine isothiocyanate, also known as TRITC is a fluorescent antibody labelling agent. It is a red-fluorescing marker and can be tracked through fluorescence microscopy. TRITC dissolves completely in DMSO at a rapid rate. And gamma globulin is unaffected to up to 30% DMSO dilution in carbonate buffer. Tetramethylrhodamine isothiocyanate doesn’t dissolve in other denaturing agents completely.

Application

Tetramethylrhodamine isothiocyanate or TRITC is used for tracking the pathway of calcium phosphate/DNA nanoparticles during cell transfection. It is an extremely intensive fluorochrome used for labeling antibodies.

Other Notes

An extremely intensive fluorochrome for labeling antibodies

Pictograms

Exclamation markHealth hazard

Signal Word

Danger

Hazard Classifications

Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

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Certificate of Origin

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