Dmitrij Golovenko et al.
Structure (London, England : 1993), 26(9), 1237-1250 (2018-07-31)
The tumor suppressor p53 acts as a transcription factor recognizing diverse DNA response elements (REs). Previous structural studies of p53-DNA complexes revealed non-canonical Hoogsteen geometry of A/T base pairs at conserved CATG motifs leading to changes in DNA shape and...
Max Michel et al.
Autophagy, 11(12), 2300-2308 (2015-08-04)
ATG101 is an essential component of the ULK complex responsible for initiating cellular autophagy in mammalian cells; its 3-dimensional structure and molecular function, however, are currently unclear. Here we present the X-ray structure of human ATG101. The protein displays an...
Jumi Park et al.
Autophagy, 16(6), 991-1006 (2019-09-13)
Armadillo (ARM) repeat proteins constitute a large protein family with diverse and fundamental functions in all organisms, and armadillo repeat domains share high structural similarity. However, exactly how these structurally similar proteins can mediate diverse functions remains a long-standing question....
Lata Govada et al.
Scientific reports, 6, 20053-20053 (2016-02-05)
Controlling crystal nucleation is a crucial step in obtaining high quality protein crystals for structure determination by X-ray crystallography. Carbon nanomaterials (CNMs) including carbon nanotubes, graphene oxide, and carbon black provide a range of surface topographies, porosities and length scales;...
MreB5 Is a Determinant of Rod-to-Helical Transition in the Cell-Wall-less Bacterium Spiroplasma.
Harne, et al.
Current Biology, 30, 4753-4762 (2020)