89270

Thymidine

≥99.0% (HPLC)

• Synonym(s): 1-(2-Deoxy-β-D-ribofuranosyl)-5-methyluracil, 1-(2-Deoxy-β-D-ribofuranosyl)thymine, 2′-Deoxythymidine, Thymine deoxyriboside, dT
• Empirical Formula (Hill Notation): C₁₀H₁₄N₂O₅
• CAS Number: 50-89-5
• Molecular Weight: 242.23
• Beilstein: 89285
• EC Number: 200-070-4
• MDL number: MFCD00006537
• PubChem Substance ID: 329769717
• NACRES: NA.51

Properties

• biological source: synthetic
• Quality Level: 200
• assay: ≥99.0% (HPLC)
• form: powder
• optical activity: [α]20/D +19±1°, c = 1% in H₂O
• mp: 185-190 °C; 186-188 °C (lit.)
• solubility: hot water: 1 g/10 mL
• SMILES string: CC1=CN([C@H]2C[C@H](O)[C@@H](CO)O2)C(=O)NC1=O
• InChI: 1S/C10H14N2O5/c1-5-3-12(10(16)11-9(5)15)8-2-6(14)7(4-13)17-8/h3,6-8,13-14H,2,4H2,1H3,(H,11,15,16)/t6-,7+,8+/m0/s1
• InChI key: IQFYYKKMVGJFEH-XLPZGREQSA-N

Description

Application

Thymidine (dT) is a pyrimidine deoxyriboside (deoxynucleoside) that upon sequential phosphorylation to deoxythymidine triphospate (dTTP) is used to synthesize DNA and the T-loop of transfer RNA. Thymidine is as substrate of Thymidine kinase EC 2.7.1.21 which phosphorylates the nucleoside with a phosphate derived from ATP. dT may be used to study the distribution, specificity and kinetics of a family of thymidine kinase(s).

Packaging

1, 5, 25 g

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves