90190
Transferrin from human blood plasma
≥95% (GE)
Synonym(s):
Human transferrin, Siderophilin
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This Item | T3309 | 616395 | T0523 |
|---|---|---|---|
| biological source human plasma | biological source human | biological source - | biological source mouse |
| assay ≥95% (GE) | assay ≥98% | assay ≥95% (SDS-PAGE) | assay ≥98% |
| technique(s) tissue culture: suitable | technique(s) cell culture | stem cell: suitable | technique(s) - | technique(s) protein quantification: suitable |
| mol wt Mr ~79550 | mol wt - | mol wt - | mol wt - |
| form powder or crystals | form powder | form lyophilized solid | form powder |
| Gene Information human ... TF(7018) | Gene Information human ... TF(7018) | Gene Information - | Gene Information mouse ... Trf(22041) |
Application
Transferrin is an important supplement in serum-free tissue culture media.
Biochem/physiol Actions
Transferrin is glycoprotein, approx. 80 kDa, with two binding sites for iron. It transports iron from its primary store in the liver to tissues that require iron, primarily bone marrow and spleen, but also brain. It binds Fe3+ extremely tightly (Kdiss 10-30 to 10-27), protecting against oxidant effects of free plasma iron.
Disclaimer
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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B. Gorinsky
Adv. Red Blood Cell Biol., D.J. Weatherall et al., eds., 7-7 (1981)
U R Goonetilleke et al.
mBio, 3(2) (2012-03-15)
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Iron transport and storage.
R R Crichton et al.
European journal of biochemistry, 164(3), 485-506 (1987-05-04)
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PLoS pathogens, 7(7), e1002104-e1002104 (2011-07-14)
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