MilliporeSigma
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91893

Sigma-Aldrich

Poly(ethylene glycol)

BioUltra, 400

Synonym(s):
PEG
Linear Formula:
H(OCH2CH2)nOH
CAS Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.26

Quality Level

product line

BioUltra

form

liquid

mol wt

Mr 380-420

impurities

insoluble matter:, passes filter test
≤0.02% peroxides (as H2O2):

refractive index

n20/D 1.467

pH

5.5-7.0 (25 °C, 50 mg/mL in H2O)

solubility

H2O: 50 mg/mL at 25 °C, clear, colorless

density

1.126 g/mL at 20 °C

anion traces

chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤50 mg/kg

cation traces

Al: ≤5 mg/kg
As: ≤0.1 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤200 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
Na: ≤300 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

λ

50 mg/mL in H2O

UV absorption

λ: 260 nm Amax: 0.06
λ: 280 nm Amax: 0.03

SMILES string

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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General description

Poly(ethylene glycol) (PEG) is a non-ionic hydrophilic polymer and is available in different molecular weights. It facilitates the purification and crystal growth of proteins and nucleic acids. PEG and dextran together result in aqueous polymer two phase system, which is required for the purification of biological materials. PEG also interacts with cell membrane, thereby allowing cell fusion.[1]

Application

Poly(ethylene glycol) (PEG) has been used to dissolve JC-124, nucleotide-binding domain, leucine rich family pyrin containing 3 gene (NLRP3) inflammasome inhibitor[2] and solubilize CoQ10, a mitochondrial coenzyme Q4.[3]

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

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Certificate of Origin

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