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95904

Sigma-Aldrich

Poly(ethylene glycol)

BioUltra, 4,000

Synonym(s):
PEG
Linear Formula:
H(OCH2CH2)nOH
CAS Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.26

Quality Level

product line

BioUltra

form

powder

mol wt

Mr 3500-4500

impurities

insoluble matter:, passes filter test
≤0.001% peroxides (as H2O2):

pH

5.5-7.0 (25 °C, 50 mg/mL in H2O)

mp

58-61 °C

solubility

H2O: 50 mg/mL at 25 °C, clear, colorless

anion traces

chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤50 mg/kg

cation traces

Al: ≤5 mg/kg
As: ≤0.1 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤200 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
Na: ≤200 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

λ

50 mg/mL in H2O

UV absorption

λ: 260 nm Amax: ≤0.10
λ: 280 nm Amax: ≤0.04

SMILES string

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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This Item
895108124081280
Poly(ethylene glycol) BioUltra, 4,000

Sigma-Aldrich

95904

Poly(ethylene glycol)

Poly(ethylene glycol) BioUltra, 8,000

Sigma-Aldrich

89510

Poly(ethylene glycol)

Poly(ethylene glycol) average Mn 4,000, platelets

Sigma-Aldrich

81240

Poly(ethylene glycol)

Poly(ethylene glycol) 10,000

Sigma-Aldrich

81280

Poly(ethylene glycol)

mol wt

Mr 3500-4500

mol wt

Mr 7000-9000

mol wt

Mn 3,500-4,500, average Mn 4,000

mol wt

8500-11500

impurities

insoluble matter:, passes filter test, ≤0.001% peroxides (as H2O2):

impurities

insoluble matter:, passes filter test, ≤0.001% peroxides (as H2O2):

impurities

-

impurities

-

mp

58-61 °C

mp

61-64 °C

mp

58-61 °C

mp

62-65 °C

cation traces

Al: ≤5 mg/kg, As: ≤0.1 mg/kg, Ba: ≤5 mg/kg, Bi: ≤5 mg/kg, Ca: ≤10 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤200 mg/kg, Li: ≤5 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Mo: ≤5 mg/kg, Na: ≤200 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Sr: ≤5 mg/kg, Zn: ≤5 mg/kg

cation traces

Al: ≤5 mg/kg, As: ≤0.1 mg/kg, Ba: ≤5 mg/kg, Bi: ≤5 mg/kg, Ca: ≤10 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤200 mg/kg, Li: ≤5 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Mo: ≤5 mg/kg, Na: ≤200 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Sr: ≤5 mg/kg, Zn: ≤5 mg/kg

cation traces

-

cation traces

-

product line

BioUltra

product line

BioUltra

product line

-

product line

-

General description

Poly(ethylene glycol) (PEG) is a polymer ethylene glycol units and is hydrophilic in nature. PEG is structurally flexible and has high hydration capacity. PEG is biocompatible and is devoid of steric hindrances in its structure. PEG is a Food and Drug Administration (FDA) approved drug conjugates. It is nonimmunogenic and safe. PEG conjugation improves solubility and dissolution of diabetes drug, Gliclazide. PEG is widely used as a reagent in biochemistry and molecular biology experiments. It is used in carbon nanotube functionalization.

Application

Poly(ethylene glycol) has been used:
  • as a component of wheat protoplast isolation and transformation buffer
  • as an additive in suspension cell culture
  • as a component of yeast transformation buffer
  • as a component of crystallization buffer in cysteine protease ATG4B crystallization

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

281.5 °F - closed cup

Flash Point(C)

138.6 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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T1503
Product Number
-
25G
Pack Size/Quantity

Additional examples:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

enter as 1.000309185)

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Genome editing of bread wheat using biolistic delivery of CRISPR/Cas9 in vitro transcripts or ribonucleoproteins
Liang Z, et al.
Nature Protocols, 13(3), 413-413 (2018)
Immunogenicity of polyethylene glycol (PEG)
Garay RP and Labaune JP
The open conference proceedings journal, 2(1), 1257-1275 (2011)
Characterisation of gliclazide-PEG 8000 solid dispersions
Biswal S, et al.
Tropical Journal of Pharmaceutical Research, 8(5), 260-260 (2009)
ATG4B contains a C-terminal LIR motif important for binding and efficient cleavage of mammalian orthologs of yeast Atg8
Rasmussen MS, et al.
Autophagy, 13(5), 834-834 (2017)
Adaptation of the Se301 insect cell line to suspension culture. Effect of turbulence on growth and on production of nucleopolyhedrovius (SeMNPV)
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Polyethylene Glycol (PEG) Selection Guide

Polyethylene glycol (PEG), also sometimes referred to as polyethylene oxide (PEO), is a condensation polymer of ethylene oxide and water that has several chemical properties that make it useful for biological, chemical and pharmaceutical applications.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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