A126

Sigma-Aldrich

(±)-HA-966

Synonym(s):
(±)-3-Amino-1-hydroxy-2-pyrrolidone
Empirical Formula (Hill Notation):
C4H8N2O2
CAS Number:
Molecular Weight:
116.12
MDL number:
PubChem Substance ID:
Pricing and availability is not currently available.

SMILES string

NC1CCN(O)C1=O

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

NONH for all modes of transport

WGK Germany

3

Melissa Nunnink et al.
Pharmacology, biochemistry, and behavior, 87(3), 321-330 (2007-06-15)
Conditioned taste aversion (CTA) is a form of associative learning in which the pairing of a taste with a toxin causes an animal to avoid the taste. NMDA receptor mediated neurotransmission has been implicated in CTA, but the role of...
Luigi Cervo et al.
Psychopharmacology, 173(1-2), 124-131 (2004-01-09)
(+)-HA-966, a partial agonist at the glycine/NMDA modulatory site, significantly reduced i.v. cocaine self-administration in a fixed-ratio (FR) schedule. Since this effect was observed studying only one dose of cocaine and considering the characteristic bell-shaped curve generated by cocaine in...
David L Walker et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 22(6), 2343-2351 (2002-03-16)
NMDA receptor antagonists block conditioned fear extinction when injected systemically and also when infused directly into the amygdala. Here we evaluate the ability of D-cycloserine (DCS), a partial agonist at the strychnine-insensitive glycine-recognition site on the NMDA receptor complex, to...
Frédéric Adam et al.
Neuropharmacology, 51(2), 191-202 (2006-05-23)
N-methyl-D-aspartate (NMDA) receptors are widely involved in opioid tolerance. However, it is less clear whether NMDA receptor antagonists reverse already-established tolerance and whether the intensity of the nociceptive stimulus influences morphine tolerance. Three days after implantation of morphine or control...
Valéria Martinez et al.
Pain, 99(3), 537-545 (2002-10-31)
Systemic opioid dosing until adequate analgesia in neuropathic pain may involve intolerable and untreatable side effects. Peripheral opioid receptor mechanisms may participate in the antinociceptive effect of systemic morphine. We evaluated the effect of peripherally injected morphine alone, and the...

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service

Social Media

LinkedIn icon
Twitter icon
Facebook Icon
Instagram Icon

MilliporeSigma

Research. Development. Production.

We are a leading supplier to the global Life Science industry with solutions and services for research, biotechnology development and production, and pharmaceutical drug therapy development and production.

© 2021 Merck KGaA, Darmstadt, Germany and/or its affiliates. All Rights Reserved.

Reproduction of any materials from the site is strictly forbidden without permission.