A1878

Sigma-Aldrich

Ala-Leu

Empirical Formula (Hill Notation):
C9H18N2O3
CAS Number:
Molecular Weight:
202.25
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.26

assay

≥99% (TLC)

Quality Level

form

powder

color

white

storage temp.

−20°C

SMILES string

CC(C)C[C@H](NC(=O)[C@H](C)N)C(O)=O

InChI

1S/C9H18N2O3/c1-5(2)4-7(9(13)14)11-8(12)6(3)10/h5-7H,4,10H2,1-3H3,(H,11,12)(H,13,14)/t6-,7-/m0/s1

InChI key

RDIKFPRVLJLMER-BQBZGAKWSA-N

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Biochem/physiol Actions

Alanyl dipeptides such as ala-leu, ala-lys, ala-gly, ala-pro, ala-tyr and ala-phe may be used in physicochemical studies or to evaluate dipeptide separation technologies. Alanyl dipeptides may also be used for studying cell uptake mechanisms, dipeptide metabolism or cell growth supplementation benefits.

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. A1878.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis
Certificate of Origin
Matthew Rosati et al.
Molecular and biochemical parasitology, 217, 7-12 (2017-08-16)
The aminopeptidase PfA-M1 is a key contributor to peptide catabolism in the human malaria parasite Plasmodium falciparum. PfA-M1 substrate specificity is shaped by the cylindrical S1 subsite, which accommodates the sidechain of the substrate P1 residue. At the top of...
Yafang Tu et al.
Molecular immunology, 121, 59-71 (2020-03-13)
Tristetraprolin (TTP) regulates inflammatory and immune responses by destabilizing target mRNAs via binding to their 3'-UTR AREs. We have recently reported that TTP preferentially up-regulates the expression level of innate immunity genes involved in the type I interferon-mediated signaling pathway...
Alice B Nongonierma et al.
Food research international (Ottawa, Ont.), 94, 79-89 (2017-03-16)
The release of dipeptidyl peptidase IV (DPP-IV) inhibitory peptides from bovine milk protein isolate (MPI) during trypsin hydrolysis was studied using a design of experiments (DOE) approach. A 3 factor×3 level DOE including temperature (40, 50 and 60°C), enzyme to...
Víctor Cruz et al.
The journal of physical chemistry. B, 115(16), 4880-4886 (2011-04-08)
An exhaustive umbrella sampling simulation of the alanine dipeptide in solution is reported. The presence of stable Y conformations in solution is assessed by both quantum calculations and experimental data from X-ray and NMR protein-solved structures available in the protein...
Trang U Vo et al.
Electrophoresis, 25(9), 1230-1236 (2004-06-03)
Series of dipeptides, including homodipeptides and alanyl dipeptides, were separated using quadruplex (G-quartet) DNA stationary phases in open-tubular capillary electrochromatography (OTCEC). The stationary phases were constructed by covalently attaching the DNA oligonucleotides to the inner capillary surface. Three different G-quartet...

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