A8597

Sigma-Aldrich

1-Amino-3,3-diethoxypropane

≥97%, liquid

Synonym(s):
3-Aminopropionaldehyde diethylacetal
Empirical Formula (Hill Notation):
C7H17NO2
CAS Number:
Molecular Weight:
147.22
MDL number:
PubChem Substance ID:
NACRES:
NA.77
Pricing and availability is not currently available.

biological source

synthetic (organic)

Quality Level

assay

≥97%

form

liquid

solubility

water: miscible

density

0.91 g/mL at 25 °C (lit.)

storage temp.

room temp

SMILES string

CCOC(CCN)OCC

InChI

1S/C7H17NO2/c1-3-9-7(5-6-8)10-4-2/h7H,3-6,8H2,1-2H3

InChI key

PXXMSHBZYAOHBD-UHFFFAOYSA-N

General description

1-Amino-3,3-diethoxypropane is an effective modulator of alginate and chitosan based hydrogels and effectively used for the delivery of bone marrow stromal cells (BMSCs) for regeneration of cartilage.

Application

1-Amino-3,3-diethoxypropane has been used:
  • with alginate in the preparation of hydrogel
  • in the generation of polyethylene glycol (PEG) polyethylenimine (PEI) polyplexes conjugate for transfection studies in hepatocellular carcinoma cell cultures
  • as a component of pH-sensitive PEG derivative for lipopolyplexes formation

Packaging

25 g in glass bottle

Pictograms

Corrosion

Signal Word

Danger

Hazard Statements

Precautionary Statements

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

UN 3267 8 / PGII

WGK Germany

WGK 3

Flash Point(F)

172.4 °F - closed cup

Flash Point(C)

78 °C - closed cup

Certificate of Analysis
Certificate of Origin
Massimiliano Magro et al.
Amino acids, 51(4), 679-690 (2019-02-07)
The preservation of enzymatic activity is a fundamental requirement for exploiting hybrid nano-bio-conjugates, and the control over protein-nanoparticle interactions, leading to stable and catalytically active hybrids, represents the key for designing new biosensing platforms. In this scenario, surface active maghemite...
Caroline R Basso et al.
Talanta, 197, 482-490 (2019-02-18)
A new immunosensor using hybrid nanomaterials for the detection of dengue virus was demonstrated in this work. This immunosensor composed of nanoparticles of γ-Fe2O3(SAMN) modified with MPA- SAMN@MPA was characterized by FTIR spectroscopy, transmission electron microscopy,quartz crystal microbalance, UV-vis and...
BMSCs laden injectable amino-diethoxypropane modified alginate-chitosan hydrogel for hyaline cartilage reconstruction
Wan W, et al.
Journal of Material Chemistry B: Materials for Biology and Medicine, 3(9), 1990-2005 (2015)
Amine-reactive pyridylhydrazone-based PEG reagents for pH-reversible PEI polyplex shielding
Fella C, et al.
European Journal of Pharmaceutical Sciences, 34(4-5), 309-320 (2008)
Pyridylhydrazone-based PEGylation for pH-reversible lipopolyplex shielding
Nie Y, et al.
Biomaterials, 32(3), 858-869 (2011)

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