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C4433

Sigma-Aldrich

Cys-Val-2-Nal-Met

≥90% (HPLC)

Empirical Formula (Hill Notation):
C26H36N4O5S2
CAS Number:
Molecular Weight:
548.72
MDL number:
PubChem Substance ID:

assay

≥90% (HPLC)

form

solid

storage temp.

−20°C

SMILES string

CSCC[C@H](NC(=O)[C@H](Cc1ccc2ccccc2c1)NC(=O)[C@@H](NC(=O)[C@@H](N)CS)C(C)C)C(O)=O

InChI

1S/C26H36N4O5S2/c1-15(2)22(30-23(31)19(27)14-36)25(33)29-21(24(32)28-20(26(34)35)10-11-37-3)13-16-8-9-17-6-4-5-7-18(17)12-16/h4-9,12,15,19-22,36H,10-11,13-14,27H2,1-3H3,(H,28,32)(H,29,33)(H,30,31)(H,34,35)/t19-,20-,21-,22-/m0/s1

InChI key

HZPSWNVHTKOMLQ-CMOCDZPBSA-N

Amino Acid Sequence

Cys-Val-Ala(2-naphthyl)-Met

Biochem/physiol Actions

p21ras farnesyltransferase inhibitor. While many tetrapeptide "inhibitors" of p21ras FTase are known, most act instead as competitive substrates. This compound is not farnesylated and is thus a true inhibitor.

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Certificate of Origin

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