C8537

Sigma-Aldrich

Z-Pro-Leu-Gly hydroxamate

≥97% (TLC)

Empirical Formula (Hill Notation):
C21H30N4O6
CAS Number:
Molecular Weight:
434.49
MDL number:
PubChem Substance ID:

assay

≥97% (TLC)

solubility

acetic acid: water (1:1): 50 mg/mL
methanol: 50 mg/mL

storage temp.

−20°C

SMILES string

CC(C)CC(NC(=O)C1CCCN1C(=O)OCc2ccccc2)C(=O)NCC(=O)NO

InChI

1S/C21H30N4O6/c1-14(2)11-16(19(27)22-12-18(26)24-30)23-20(28)17-9-6-10-25(17)21(29)31-13-15-7-4-3-5-8-15/h3-5,7-8,14,16-17,30H,6,9-13H2,1-2H3,(H,22,27)(H,23,28)(H,24,26)

InChI key

VVGFLHRPYCTXGJ-UHFFFAOYSA-N

Amino Acid Sequence

Z-Pro-Leu-Gly

Biochem/physiol Actions

A hydroxamate inhibitor of human collagenases (MMP-1; matrix metalloproteinase 1). It is a substrate analog that interacts with the zinc moiety of MMP-1.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

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