D5764

Sigma-Aldrich

2,3-Diphospho-D-glyceric acid pentasodium salt

glycolysis metabolite

Synonym(s):
2,3-DPG, D-Glycerate 2,3-diphosphate sodium salt
Linear Formula:
C3H3O10P2Na5
CAS Number:
Molecular Weight:
375.95
MDL number:
PubChem Substance ID:
NACRES:
NA.25

Quality Level

biological source

synthetic

form

powder

impurities

3-phosphoglyceric acid, essentially free

storage temp.

−20°C

SMILES string

[Na].OC(=O)[C@@H](COP(O)(O)=O)OP(O)(O)=O

InChI

1S/C3H8O10P2.Na.H/c4-3(5)2(13-15(9,10)11)1-12-14(6,7)8;;/h2H,1H2,(H,4,5)(H2,6,7,8)(H2,9,10,11);;/t2-;;/m1../s1

InChI key

JJEMSNINYKJOBZ-YBBRRFGFSA-N

Related Categories

Application

D-Glycerate 2,3-diphosphate, cofactor of both phosphoglyceric acid mutase and hemoglobin, may be used as a reference compound in analysis of blood cell (erythrocyte) glycolysic cycle metabolites.

Packaging

25, 100, 500 mg in poly bottle

Biochem/physiol Actions

Metabolite of glycolysis within human erythrocytes produced by 2,3-diphosphoglycerate mutase in an alternative to the glycolytic pathway. Binds to hemaglobin to reduce oxygenation.

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

Chiara Crestani et al.
Journal of veterinary internal medicine, 32(3), 1051-1059 (2018-04-11)
Optimal procedure for storage of feline blood is needed. Open-collection systems have been employed in feline medicine, thus limiting the possibility for storage. To evaluate indicators of quality of feline blood stored for 35 days at +4°C in a closed-collection...
Minke A E Rab et al.
American journal of hematology, 94(5), 575-584 (2019-02-21)
In sickle cell disease (SCD), sickle hemoglobin (HbS) polymerizes upon deoxygenation, resulting in sickling of red blood cells (RBCs). These sickled RBCs have strongly reduced deformability, leading to vaso-occlusive crises and chronic hemolytic anemia. To date, there are no reliable...
Manon Bardyn et al.
Metabolites, 10(6) (2020-06-04)
After blood donation, the red blood cells (RBCs) for transfusion are generally isolated by centrifugation and then filtrated and supplemented with additive solution. The consecutive changes of the extracellular environment participate to the occurrence of storage lesions. In this study...
H Gulliksson et al.
Vox sanguinis, 112(1), 33-39 (2016-12-22)
The present general plasticizer di-2-ethylhexyl-phthalate in polyvinylchloride (PVC) blood bags is only physically dispersed in PVC and will therefore leach into blood components. The objective of this study was to perform a first preliminary red blood cell (RBC) storage evaluation...
Ida Stangerup et al.
Transfusion, 57(8), 1905-1911 (2017-04-30)
No former studies have examined how blood donation influences physical performance in women, who due to menstruation may have a slower recovery of performance. Therefore, the aim of this study was to clarify how VO VO VO VO

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