E1001

Sigma-Aldrich

Ethisterone

≥99% (HPLC)

Synonym(s):
17β-Hydroxy-4,17α-pregnen-20-yn-3-one, 4,17α-Pregnen-17β-ol-20-yn-3-one, 17α-Ethynyltestosterone
Empirical Formula (Hill Notation):
C21H28O2
CAS Number:
Molecular Weight:
312.45
Beilstein/REAXYS Number:
1889895
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.77
Pricing and availability is not currently available.

Quality Level

biological source

synthetic (organic)

sterility

non-sterile

assay

≥99% (HPLC)

form

powder

drug control

regulated under CDSA - not available from Sigma-Aldrich Canada

application(s)

cell culture | mammalian: suitable

mp

263-269 °C (lit.)

solubility

chloroform: methanol (1:1): 20 mg/mL, clear to slightly hazy, colorless to light yellow

originator

Novartis

shipped in

ambient

storage temp.

room temp

SMILES string

C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2CC[C@@]4(C)[C@H]3CC[C@@]4(O)C#C

InChI

1S/C21H28O2/c1-4-21(23)12-9-18-16-6-5-14-13-15(22)7-10-19(14,2)17(16)8-11-20(18,21)3/h1,13,16-18,23H,5-12H2,2-3H3/t16-,17+,18+,19+,20+,21+/m1/s1

InChI key

CHNXZKVNWQUJIB-CEGNMAFCSA-N

Looking for similar products? Visit Product Comparison Guide

General description

Ethisterone is a progestogen. It is a danazol derivative.

Application

Ethisterone has been used as a component in Dulbecco′s modified eagle medium (DMEM) to culture the transfected COS-7 cell for transient transfection assay and gene transfection assay.

Packaging

25, 100 g in glass bottle

Biochem/physiol Actions

Ethisterone acts as a progestational agent. It is consumed by pregnant mothers to prevent miscarriage.

Features and Benefits

This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Pictograms

Health hazardEnvironment

Signal Word

Danger

Hazard Statements

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Ambiguous Genitalia in the Newborn
Avery's Diseases of the Newborn, 1286-1306 (2012)
Evolutionary History and Functional Characterization of Androgen Receptor Genes in Jawed Vertebrates
Ogino Y, et al.
Endocrinology, 150(12), 5415-5427 (2009)
Hypothalamic, pituitary and sex hormones
Clinical Pharmacology, 596-614 (2012)
Junsu Kang et al.
Developmental cell, 27(1), 19-31 (2013-10-19)
Precise spatiotemporal regulation of signaling activators and inhibitors can help limit developmental crosstalk between neighboring tissues during morphogenesis, homeostasis, and regeneration. Here, we find that the secreted Wnt inhibitor Dkk1b is abundantly produced by dense regions of androgen-regulated epidermal tubercles...
Cloning and expression analysis of androgen receptor gene in chicken embryogenesis
Katoh H, et al.
Febs Letters, 580(6), 1607-1615 (2006)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service

Social Media

LinkedIn icon
Twitter icon
Facebook Icon
Instagram Icon

MilliporeSigma

Research. Development. Production.

We are a leading supplier to the global Life Science industry with solutions and services for research, biotechnology development and production, and pharmaceutical drug therapy development and production.

© 2021 Merck KGaA, Darmstadt, Germany and/or its affiliates. All Rights Reserved.

Reproduction of any materials from the site is strictly forbidden without permission.