All Photos(3)

G6761

Sigma-Aldrich

Glycine sodium salt hydrate

≥99% (HPLC)

Linear Formula:
H2NCH2CO2Na · xH2O
CAS Number:
Molecular Weight:
97.05 (anhydrous basis)
MDL number:
eCl@ss:
32160406
PubChem Substance ID:

Quality Level

assay

≥99% (HPLC)

mp

197-201 °C (lit.)

SMILES string

[Na+].[H]O[H].NCC([O-])=O

InChI

1S/C2H5NO2.Na.H2O/c3-1-2(4)5;;/h1,3H2,(H,4,5);;1H2/q;+1;/p-1

InChI key

CIJQGPVMMRXSQW-UHFFFAOYSA-M

Looking for similar products? Visit Product Comparison Guide

General description

Glycine is synthesized from choline, threonine and serine. It serves as a precursor for porphyrins, purines, glutathione and creatine.

Application

Glycine sodium salt hydrate has been used as a component of buffer for homogenization of whole muscle for protein extraction and in electrophoresis buffer. It has also been used as a neurotransmitter in immunohistochemical staining of Zebrafish spinal cord sections.
Glycine sodium salt hydrate has been used for homogenization of muscle tissue and as a component of buffer for electrophoresis, for analysis of whole muscle proteins obtained from five ariid catfish species: Ariopsis felis, Bagre marinus, Cathorops aguadulce, Cathorops fuerthii and Ariopsis guatemalensis.

Packaging

1 kg in poly drum
100, 500 g in poly bottle

Biochem/physiol Actions

Glycine is essential for the regulation immune function, metabolism, growth and development. It modulates intracellular Ca2+ levels and cytokines production. A reduction in glycine levels is observed in obesity, type 2 diabetes (T2DM), and non-alcoholic fatty liver disease (NAFLDs). Glycine is degraded to serine by glycine serine hydroxymethyltransferase 1 in cytoplasm.

Storage Class Code

13 - Non Combustible Solids

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

Complementary expression of calcium binding proteins delineates the functional organization of the locomotor network
Berg EM, et al.
Brain Structure &Amp; Function, 223(5), 2181-2196 (2018)
Phylogenetic relationships among five marine Catfish species (Pisces: Ariidae) from Mexico
Tenorio-Colin G, et al.
Hidrobiologica, 20(3), 266-274 (2010)
Multifarious beneficial effect of nonessential amino acid, glycine: a review
Razak MA, et al.
Oxidative Medicine and Cellular Longevity, 2017 (2017)
Glycine Metabolism and Its Alterations in Obesity and Metabolic Diseases
Alves A, et al.
Nutrients, 11(6), 1356-1356 (2019)
J W Johnson et al.
Nature, 325(6104), 529-531 (1987-02-05)
Transmitters mediating 'fast' synaptic processes in the vertebrate central nervous system are commonly placed in two separate categories that are believed to exhibit no interaction at the receptor level. The 'inhibitory transmitters' (such as glycine and GABA) are considered to...

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service