Chandradeo Narayan et al.
Journal of carcinogenesis, 11, 9-9 (2012-08-25)
Lung cancer is a leading cause of cancer death. There has been found a substantial gap in the understanding of lung cancer genesis at the molecular level. We developed urethane (ethyl carbamate) induced lung tumor mice model to understand the...
Luiza A de Castro-Jorge et al.
PLoS pathogens, 15(9), e1007934-e1007934 (2019-09-04)
Mayaro virus (MAYV) is an arbovirus that circulates in Latin America and is emerging as a potential threat to public health. Infected individuals develop Mayaro fever, a severe inflammatory disease characterized by high fever, rash, arthralgia, myalgia and headache. The...
Nanshan Song et al.
Biochemical pharmacology, 150, 245-255 (2018-02-16)
β2-Aderenergic receptor (β2AR) agonist, Salmeterol exhibits anti-inflammatory activities. However, the inhibitory effects of Salmeterol on inflammasome activation are elusive and the underlying mechanisms need to be explored. In this study, we established inflammatory model in primary bone marrow-derived macrophages (BMDM)...
Baojin Chi et al.
Experimental and therapeutic medicine, 15(1), 847-853 (2018-02-06)
For several thousand years
Manoranjan Sahoo et al.
TheScientificWorldJournal, 11, 2037-2050 (2011-11-30)
The inflammasome is an important innate immune pathway that regulates at least two host responses protective against infections: (1) secretion of the proinflammatory cytokines IL-1β and IL-18 and (2) induction of pyroptosis, a form of cell death. Inflammasomes, of which...