L3877

Sigma-Aldrich

D-Leu-Tyr

Empirical Formula (Hill Notation):
C15H22N2O4
CAS Number:
Molecular Weight:
294.35
MDL number:
PubChem Substance ID:

storage temp.

−20°C

SMILES string

CC(C)C[C@@H](N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O

InChI

1S/C15H22N2O4/c1-9(2)7-12(16)14(19)17-13(15(20)21)8-10-3-5-11(18)6-4-10/h3-6,9,12-13,18H,7-8,16H2,1-2H3,(H,17,19)(H,20,21)/t12-,13+/m1/s1

InChI key

LHSGPCFBGJHPCY-OLZOCXBDSA-N

Biochem/physiol Actions

D-Leucyltyrosine (D-Leu-Tyr) may be used to support the study of the uptake of oligopeptides by various peptide transport mechanisms.

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis
Certificate of Origin
H Daniel et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 9(11), 1112-1117 (1995-08-01)
Based on the involvement of zinc in hydrolysis of peptides, we hypothesized that Zn2+ may also play a role in peptide transport. To investigate this hypothesis, kidney brush border membrane vesicles (BBMV) were incubated for 30 min with different concentrations...
J A Krause et al.
Acta crystallographica. Section B, Structural science, 49 ( Pt 1), 123-130 (1993-02-01)
L-Leu-L-Tyr, (I), C15H22N2O4, M(r) = 294.35, crystallizes from MeOH/5% dimethyl sulfoxide in the orthorhombic space group P2(1)2(1)2(1). a = 5.644 (1), b = 12.094 (3), c = 22.548 (4) A, V = 1539.0 (5) A3, Z = 4, Dx =...
Pedro Lameiras et al.
Journal of magnetic resonance (San Diego, Calif. : 1997), 212(1), 161-168 (2011-08-02)
NMR of weakly polar analytes in an apolar ultraviscous solvent has recently been proposed for mixture analysis as a pertinent alternative to the DOSY experiment. The present article reports the first use of glycerol and glycerol carbonate as polar solvents...
Conceição Fonseca et al.
Journal of mass spectrometry : JMS, 44(5), 681-693 (2009-01-07)
The exposure of peptides and proteins to reactive hydroxyl radicals results in covalent modifications of amino acid side-chains and protein backbone. In this study we have investigated the oxidation the isomeric peptides tyrosine-leucine (YL) and leucine-tyrosine (LY), by the hydroxyl...
Pedro Domingues et al.
Biomedical chromatography : BMC, 26(1), 51-60 (2011-03-25)
Free radical species are generally short-lived due to their high reactivity and thus direct measurement and identification are often impossible. In this study we used a spin trap, 5,5-dimethyl-1-pyrroline-N-oxide (DMPO), to trap radical intermediates formed during the oxidation of isomeric...

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