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L6401

Sigma-Aldrich

Lacto-N-fucopentaose II

from human milk, ≥98% (HPAE/PAD)

Synonym(s):
Lewis-a pentasaccharide, β-D-Gal-(1→3)-(α-L-Fuc-[1→4])-β-D-GlcNAc-(1→3)-β-D-Gal-(1→4)-D-Glc, LNFP II, Lea-Lactose
Empirical Formula (Hill Notation):
C32H55NO25
CAS Number:
Molecular Weight:
853.77
Beilstein:
6050703
MDL number:

biological source

human milk

assay

≥98% (HPAE/PAD)

storage temp.

2-8°C

SMILES string

C[C@@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](NC(C)=O)[C@@H](O[C@@H]2CO)O[C@H]3[C@@H](O)[C@@H](CO)O[C@@H](O[C@@H]4[C@@H](CO)OC(O)[C@H](O)[C@H]4O[C@@H]5O[C@H](CO)[C@H](O)[C@H](O)[C@H]5O)[C@@H]3O)[C@@H](O)[C@H](O)[C@@H]1O

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Certificate of Analysis

Certificate of Origin

Alexander Pirkl et al.
Analytical chemistry, 84(13), 5669-5676 (2012-06-08)
Although water ice has been utilized in the past as a matrix for infrared matrix-assisted laser desorption/ionization mass spectrometry (IR-MALDI-MS), it has not found a wider use due to limitations in the analytical performance and technical demands on the employment...
Q Xu et al.
Glycobiology, 6(3), 281-288 (1996-04-01)
Three-bond heteronuclear coupling constants (3JCH) are extremely useful in describing flexible models for oligosaccharides. We show that antiphase methods for measuring 3JCH in oligosaccharides have limited reliability but that the coupling constants can be reliably measured in natural abundance by...
Jens Soltwisch et al.
Analytical chemistry, 81(8), 2921-2934 (2009-03-24)
Matrix-assisted laser desorption ionization (MALDI) allows for the mass spectrometric (MS) analysis of thermally labile, non-volatile biomolecules. However, some residual analyte fragmentation typically accompanies the phase transition from the condensed to the gas phase and following plume expansion, even under...
R W Loveless et al.
The Biochemical journal, 258(1), 109-113 (1989-02-15)
Carbohydrate recognition by bovine serum conglutinin has been investigated by inhibition and direct binding assays using glycoproteins and polysaccharides from Saccharomyces cerevisiae (baker's yeast), and neoglycolipids derived from N-acetylglucosamine oligomers, mannobiose and human milk oligosaccharides. The results clearly show that...
J Alexander et al.
Journal of immunology (Baltimore, Md. : 1950), 164(3), 1625-1633 (2000-01-21)
Linear carbohydrate-peptide constructs based on the 13 amino acid nonnatural pan DR epitope (PADRE) and carbohydrate B cell epitopes are demonstrated to be potent immunogens. These data support our belief that PADRE should be considered as an alternative to more...

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