MilliporeSigma
All Photos(1)

P3168

Sigma-Aldrich

Phytic acid dodecasodium salt hydrate

≥90%, from rice

Synonym(s):
InsP6, myo-Inositol hexakis(dihydrogen phosphate), Inositol hexaphosphoric acid, Inositol hexakisphosphate
Empirical Formula (Hill Notation):
C6H6Na12O24P6 · xH2O
CAS Number:
Molecular Weight:
923.82 (anhydrous basis)
MDL number:

biological source

rice

assay

≥90%

SMILES string

[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[H]O[H].[O-]P([O-])(=O)O[C@H]1[C@H](OP([O-])([O-])=O)[C@H](OP([O-])([O-])=O)[C@H](OP([O-])([O-])=O)[C@@H](OP([O-])([O-])=O)[C@@H]1OP([O-])([O-])=O

Biochem/physiol Actions

Phytic acid is present in all eukaryotic cells. In plants, it is known to function as a [PO4]3− storage depot and precursor for other inositol phosphates and pyrophosphates. Its high surface negative charge makes it a potent chelator of divalent and trivalent cations in vitro, and it is most likely associated with Ca2+ or Mg2+ ions in vivo. In yeast, phytic acid acts with the nuclear pore protein Gle1 to regulate the nuclear export of mRNA by coactivating the RNA-dependent ATPase activity of DExD-box protein 5 (Dbp5).

Quality

Contains minute amounts of black particles.

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

Andreia Biolo et al.
Proceedings of the National Academy of Sciences of the United States of America, 106(6), 1926-1929 (2009-02-11)
A major determinant of maximal exercise capacity is the delivery of oxygen to exercising muscles. myo-Inositol trispyrophosphate (ITPP) is a recently identified membrane-permeant molecule that causes allosteric regulation of Hb oxygen binding affinity. In normal mice, i.p. administration of ITPP

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service