P6762

Sigma-Aldrich

Poly-L-aspartic acid sodium salt

mol wt 15,000-50,000

Synonym(s):
Poly(L-aspartic acid) sodium salt
CAS Number:
MDL number:
PubChem Substance ID:

mol wt

15,000-50,000

storage temp.

−20°C

SMILES string

NC(CC(O)=O)C(=O)O[Na]

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Analysis Note

Molecular weight based on viscosity.

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Nam Muk Oh et al.
Colloids and surfaces. B, Biointerfaces, 101, 298-306 (2012-09-27)
Advanced materials that have controllable pH-responsive properties when submerged in the lysosome have a great potential in intracellular drug delivery. We developed novel poly(L-amino acid) nanogels that were prepared by a facile cross-linking of poly[L-aspartic acid-g-(3-diethylaminopropyl)]-b-poly(ethylene glycol)-maleimide [poly(L-Asp-g-DEAP)-b-PEG-Mal] and poly(L-aspartic...
Kyung Hyun Min et al.
Biomaterials, 33(23), 5788-5797 (2012-05-18)
A mineral (calcium phosphate, CaP)-reinforced core-shell-corona micelle was evaluated as a nanocarrier of doxorubicin (DOX) for cancer therapy. The polymer micelles of poly(ethylene glycol)-b-poly(L-aspartic acid)-b-poly(L-phenylalanine) (PEG-PAsp-PPhe) in the aqueous phase provided the three distinct functional domains: the hydrated PEG outer...
Chao Li et al.
Bioconjugate chemistry, 23(9), 1832-1837 (2012-08-09)
Genome manipulation controlled by small metal complexes has attracted extensive interest because of their potential application in the fields of molecular biotechnology and drug development. However, their medicinal application is still limited due to the distinct toxicity of the free...
Anna Kubíčková et al.
Physical review letters, 108(18), 186101-186101 (2012-06-12)
Charge reversal as an extreme case of charge compensation is directly observed by capillary electrophoresis for a negatively charged peptide in aqueous solutions of trivalent cations. Atomistic and coarse-grained simulations provide molecular interpretation of this effect showing that it is...
Ruijun Xing et al.
Nanoscale, 3(12), 4943-4945 (2011-11-09)
We report in this communication a simple, facile surface modification strategy to transfer hydrophobic manganese oxide nanoparticles (MONPs) into water by using polyaspartic acid (PASP). We systematically investigated the effect of the size of PASP-MONPs on MRI of normal liver...

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