P7081

Sigma-Aldrich

1,2-Didecanoyl-sn-glycero-3-phosphocholine

≥99% (TLC)

Synonym(s):
Didecanoyllecithin, 3-sn-Phosphatidylcholine, 1,2-didecanoyl, (7R)-4-Hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxodecyl)oxy]-3,5,9-trioxa-4-phosphanonadecan-1-aminium 4-oxide, inner salt, PC, PC(10:0/10:0), 1,2-Dicaprinoyl-sn-glycero-3-phosphocholine, L-α-Phosphatidylcholine, didecanoyl
Empirical Formula (Hill Notation):
C28H56NO8P
CAS Number:
Molecular Weight:
565.72
Beilstein/REAXYS Number:
3757665
MDL number:
PubChem Substance ID:

Quality Level

assay

≥99% (TLC)

form

powder

functional group

phospholipid

shipped in

ambient

storage temp.

−20°C

SMILES string

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCC)=O)COC(CCCCCCCCC)=O)=O

InChI

1S/C28H56NO8P/c1-6-8-10-12-14-16-18-20-27(30)34-24-26(25-36-38(32,33)35-23-22-29(3,4)5)37-28(31)21-19-17-15-13-11-9-7-2/h26H,6-25H2,1-5H3/t26-/m1/s1

InChI key

MLKLDGSYMHFAOC-AREMUKBSSA-N

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NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

Effect of absorption enhancers on ciliated epithelium: a novel in vivo toxicity screening method using rotifers.
E Adriaens et al.
Pharmaceutical research, 14(4), 541-545 (1997-04-01)
Cécile Loudet et al.
Biochimica et biophysica acta, 1724(3), 315-323 (2005-06-18)
Mixtures of dicaproyl- (DC), dimyristoyl- (DM) and 1-tetradecanoyl-2-biphenylbutanoyl-(TBB) phosphatidylcholine (PC) in water produce bicelle membranes that are oriented by magnetic fields. DMPC/DCPC systems orient such that their membrane plane is parallel to the magnetic field, whereas for TBBPC/DCPC, the plane...
C Agerholm et al.
Journal of pharmaceutical sciences, 83(12), 1706-1711 (1994-12-01)
The transepithelial transport of biosynthetic human growth hormone (hGH) formulated with the absorption enhancers didecanoyl-L-alpha-phosphatidylcholine (DDPC) and alpha-cyclodextrin (alpha-CD) was studied after intranasal administration to rabbits. Plasma concentrations of the hormone were determined until 240 min post administration by ELISA...
Vivek S Purohit et al.
The AAPS journal, 8(2), E362-E370 (2006-06-27)
Replacement therapy with exogenous recombinant factor VIII (rFVIII) to control bleeding episodes results in the development of inhibitory antibodies in 15% to 30% of hemophilia A patients. The inhibitory antibodies are mainly directed against specific and universal immunodominant epitopes located...
Qunfeng Zhang et al.
Tree physiology, 41(2), 317-330 (2020-10-27)
It is well known that green tea made from fully developed leaves located at the base of young shoots is of lower quality than that made from the still developing leaves located on the top of the shoot. It has...

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