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P7505

Sigma-Aldrich

Putrescine dihydrochloride

≥98% (TLC)

Synonym(s):
1,4-Butanediamine dihydrochloride, 1,4-Diaminobutane dihydrochloride, Tetramethylenediamine dihydrochloride
Linear Formula:
NH2(CH2)4NH2 · 2HCl
CAS Number:
Molecular Weight:
161.07
Beilstein:
3906680
EC Number:
MDL number:
PubChem Substance ID:

Quality Level

assay

≥98% (TLC)

form

powder

mp

280 °C (dec.) (lit.)

solubility

H2O: soluble 100 mg/mL, clear, colorless

SMILES string

Cl[H].Cl[H].NCCCCN

InChI

1S/C4H12N2.2ClH/c5-3-1-2-4-6;;/h1-6H2;2*1H

InChI key

XXWCODXIQWIHQN-UHFFFAOYSA-N

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Application

Putrescine dihydrochloride has been used:
  • as a bioactive amine standard in high-performance liquid chromatography (HPLC)
  • as a component of hormone mix supplemented to Dulbecco′s modified eagle medium (DMEM) to study its effects on neural stem cells
  • as a supplement in DMEM for culturing of endometrial cancer cells

Biochem/physiol Actions

Putrescine is an aliphatic amine and is positively charged. It acts as a precursor of spermine and plays a role in polyamine biosynthesis. Putrescine is found in several plants, animals, and bacteria. It plays a role in cell proliferation and cell growth in Escherichia coli. Putrescine is a component of agrochemicals, surfactants, pharmaceuticals, polymers, and additives.
Binds to the polyamine modulatory site of the NMDA receptor and potentiates NMDA-induced currents; precursor of spermidine.

Pictograms

CorrosionSkull and crossbones

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B

Storage Class Code

6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 1

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

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Certificate of Origin

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