V3265

Sigma-Aldrich

VU0029767

≥98% (HPLC)

Synonym(s):
(E)-2-(4-Ethoxyphenylamino)-N′-((2-hydroxynaphthalen-1-yl)methylene)acetohydrazide
Empirical Formula (Hill Notation):
C21H21N3O3
CAS Number:
Molecular Weight:
363.41
MDL number:
PubChem Substance ID:

assay

≥98% (HPLC)

form

powder

color

gray-brown

solubility

DMSO: >10 mg/mL

storage temp.

room temp

SMILES string

CCOc1ccc(NCC(=O)N\N=C\c2c(O)ccc3ccccc23)cc1

InChI

1S/C21H21N3O3/c1-2-27-17-10-8-16(9-11-17)22-14-21(26)24-23-13-19-18-6-4-3-5-15(18)7-12-20(19)25/h3-13,22,25H,2,14H2,1H3,(H,24,26)/b23-13+

InChI key

JWRJGCUSLSJMMD-YDZHTSKRSA-N

Biochem/physiol Actions

VU0029767 is a selective, positive allosteric modulator at the muscarinic M1 acetylcholine receptor. It shifts concentration-dependent response to acetylcholine at least five-fold, but does not compete at the ACh binding site. VU0029767 also potentiates the effects of allosteric agonist TBPB.

Pictograms

Exclamation markEnvironment

Signal Word

Warning

Hazard Statements

Precautionary Statements

RIDADR

UN 3077 9 / PGIII

WGK Germany

3

Certificate of Analysis
Certificate of Origin

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