A0278

Sigma-Aldrich

L-Ascorbic acid

reagent grade

Synonym(s):
Antiscorbutic factor, Vitamin C, L-Threoascorbic acid
Empirical Formula (Hill Notation):
C6H8O6
CAS Number:
Molecular Weight:
176.12
Beilstein/REAXYS Number:
84272
EC Number:
MDL number:
PubChem Substance ID:

Quality Level

biological source

synthetic

grade

reagent grade

assay

≥98% (with Iodine, titration)

form

powder

application(s)

HPLC: suitable

color

white to light yellow

pH

1.0-2.5 (25 °C, 176 g/L in water)

mp

190-194 °C (dec.)

solubility

water: soluble 50 mg/mL

SMILES string

OC([C@]([C@@H](O)CO)([H])O1)=C(O)C1=O

InChI

1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1

InChI key

CIWBSHSKHKDKBQ-JLAZNSOCSA-N

Gene Information

human ... SLC23A2(9962)

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General description

Ascorbic Acid, also known as Vitamin C, is a six-carbon lactone produced by plants and some animal species but not by humans and other primates. It is a water-soluble vitamin.

Application

L-Ascorbic acid may be used as standard in assay for erythrocyte hemolysis mediated by peroxyl free radicals. It may be used for the reduction of graphene oxide sheets.
L-Ascorbic acid has been used as a standard in high performance liquid chromatography (HPLC) for quantification of L-ascorbic acid.

Packaging

25, 100, 500 g in glass bottle
1 kg in glass bottle

Biochem/physiol Actions

L-ascorbic acid modified poly(ester urethane)s might facilitate soft tissue regeneration. It also helps in increasing iron absorption by tissues. In addition, it aids in tyrosine metabolism and microsomal drug metabolism.
L-Ascorbic acid is an anti-oxidant. L-Ascorbic acid (vitamin C) is important for many enzymatic reactions for maintaining prosthetic metal ions in their reduced forms (for example, Fe2+, Cu+). It protects tissues from oxidative damage by scavenging free radicals. It has mild reductive ability and nontoxic property. It is commonly employed reductant in the laboratory. Colorimetric determination of ascorbic acid in plasma using acid phosphotungstate has been reported.

Caution

May darken in storage.

storage_class_code

13 - Non Combustible Solids

WGK Germany

WGK 1

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

Dehydrofreezing of pineapple
Ramallo LA and Mascheroni RH
Journal of Food Engineering, 99(3), 269-275 (2010)
Jk Psc Quick Review for Medical Officers: A Useful Manual For NEET, AIIMS and PGI Md/Ms. Entrance Exams (2018)
Synthesis and characterization of cycloaliphatic hydrophilic polyurethanes, modified with L-ascorbic acid, as materials for soft tissue regeneration
Kucinska-Lipka J, et al.
Materials Science & Engineering. C, Materials For Biological Applications, 75(3), 671-681 (2017)
T R Tickner et al.
Clinica chimica acta; international journal of clinical chemistry, 85(2), 125-129 (1978-04-17)
A new colorimetric method for the assay of biliverdin in biological fluids is described. The method, based upon the reaction of biliverdin with barbituric acid, offers improved sensitivity and selectivity when compared to direct spectrophotometric measurements. Using this method biliverdinaemia...
Total phenols, ascorbic acid, β-carotene and lycopene in Portuguese wild edible mushrooms and their antioxidant activities.
Barros L, et al.
Food Chemistry, 103(2), 413-419 (2007)

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