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A111060

Sigma-Aldrich

DMT-dA(bz) Phosphoramidite

configured for ABI 39X

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Synonym(s):
DMT-dA(bz) Amidite, N-benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxyadenosine, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite], N6-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyadenosine-3′-O-[O-(2-cyanoethyl)-N,N′-diisopropylphosphoramidite]
Empirical Formula (Hill Notation):
C47H52N7O7P
CAS Number:
Molecular Weight:
857.93
MDL number:
PubChem Substance ID:
NACRES:
NA.51

biological source

non-animal source (no BSE/TSE risk)

description

color-coded label

type

for DNA synthesis

product line

Proligo Reagents

assay

≥99% (31P-NMR)
≥99.0% (reversed phase HPLC)

form

powder or granules

technique(s)

oligo synthesis: suitable

impurities

≤0.3 wt. % water content (Karl Fischer)

color

white to off-white

λ

conforms (UV/VIS Identity)

compatibility

configured for ABI 39X

nucleoside profile

base: deoxyadenosine
base protecting group: benzoyl
2' protecting group: none
5' protecting group: DMT
deprotection: standard

storage temp.

2-8°C

SMILES string

COc1ccc(cc1)C(OC[C@H]2O[C@H](C[C@@H]2OP(OCCC#N)N(C(C)C)C(C)C)n3cnc4c(NC(=O)c5ccccc5)ncnc34)(c6ccccc6)c7ccc(OC)cc7

InChI

1S/C47H52N7O7P/c1-32(2)54(33(3)4)62(59-27-13-26-48)61-40-28-42(53-31-51-43-44(49-30-50-45(43)53)52-46(55)34-14-9-7-10-15-34)60-41(40)29-58-47(35-16-11-8-12-17-35,36-18-22-38(56-5)23-19-36)37-20-24-39(57-6)25-21-37/h7-12,14-25,30-33,40-42H,13,27-29H2,1-6H3,(H,49,50,52,55)/t40-,41+,42+,62?/m0/s1

InChI key

GGDNKEQZFSTIMJ-AKWFTNRHSA-N

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This Item
A111080A111040A111050
vibrant-m

A111060

DMT-dA(bz) Phosphoramidite

vibrant-m

A111080

DMT-dA(bz) Phosphoramidite

vibrant-m

A111040

DMT-dA(bz) Phosphoramidite

vibrant-m

A111050

DMT-dA(bz) Phosphoramidite

biological source

non-animal source (no BSE/TSE risk)

biological source

non-animal source (no BSE/TSE risk)

biological source

non-animal source (no BSE/TSE risk)

biological source

non-animal source (no BSE/TSE risk)

color

white to off-white

color

white to off-white

color

white to off-white

color

white to off-white

impurities

≤0.3 wt. % water content (Karl Fischer)

impurities

≤0.3 wt. % water content (Karl Fischer)

impurities

≤0.3 wt. % water content (Karl Fischer)

impurities

≤0.3 wt. % water content (Karl Fischer)

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

form

powder or granules

form

powder or granules

form

powder or granules

form

powder or granules

General description

DMT-dA(bz) Phosphoramidite belongs to the DNA Phosphoramidites group.The key features of standard protected DNA phosphoramidite are:
  • Exocyclic amine functions are protected by a benzoyl group (dA(bz) and dC(bz)) or isobutyryl group (dG(ib))
  • Recommended cleavage and deprotection conditions are 8 hours at 55 °C or 24 hours at room temperature using concentrated ammonia solution for standard base-protected oligonucleotides
  • The high coupling efficiency of Proligo′s DNA phosphoramidites leads to high-yield and high-quality oligonucleotides

Packaging

packaged in a 60 ml septum bottle

Legal Information

ABI is a trademark of Applera Corporation or its subsidiaries in the US and/or certain other countries

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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