A1900

Sigma-Aldrich

Albumin, Monomer bovine

Monomer ≥97 %

CAS Number:
EC Number:
MDL number:
eCl@ss:
42010201
NACRES:
NA.26

Quality Level

biological source

bovine

assay

≥97% (PAGE)

form

lyophilized powder

composition

Monomer, ≥97%

solubility

H2O: soluble 50 mg/mL

UniProt accession no.

storage temp.

2-8°C

Gene Information

bovine ... ALB(280717)

General description

The most abundant plasma protein in mammals is albumin. It is produced in the liver and transferred as a non-glycosylated protein into the plasma. This multifunctional protein can bind to ligands.

Application

The binding properties of albumin can be used for a wide range of clinical, pharmaceutical, and biochemical applications.
Albumin, Monomer bovine has been used as a:
  • molecular weight (MW) and polydispersion index (PDI) reference standard for the analysis of hyaluronic acid (HA)-based eye drops
  • standard in multi-angle light scattering coupled with size exclusion chromatography (SEC-MALS) for calibration
  • model protein to generate subvisible particles (SVPs) for flow imaging microscopy studies

Packaging

250, 500 mg in poly bottle
1 g in poly bottle

Biochem/physiol Actions

Albumin is the most important circulatory protein involved in the control of Ca2+ (and Mg2+) levels in mammals.

Preparation Note

Isolated from albumin (A4503) as described for mercaptalbumin in Janatova, J., et al., J. Biol. Chem., 243, 3612 (1968).

storage_class_code

11 - Combustible Solids

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

null
Surendra Dasari et al.
Journal of proteome research, 8(3), 1263-1270 (2009-01-29)
A robust peptide quantification method was developed where overlapping peptide isotopic distributions were fit with predicted peptide isotopic envelope mixture models (IEMMs). Application to two difficult quantitative problems was demonstrated. The first was the quantification of deamidation, where masses of...
Yu Isakari et al.
Biotechnology journal, 13(7), e1700738-e1700738 (2018-02-03)
Combining chemical reaction with separation offers several advantages. In this work possibility to induce spontaneous desorption of adsorbed macromolecules, once being PEGylated, through adjustment of the reagent composition is investigated. Bovine serum albumin (BSA) and activated oligonucleotide, 9T, are used...
Mingshan Li et al.
Protein science : a publication of the Protein Society, 29(2), 443-454 (2019-10-28)
Methylation of specific chemoreceptor glutamyl residues by methyltransferase CheR mediates sensory adaptation and gradient sensing in bacterial chemotaxis. Enzyme action is a function of chemoreceptor signaling conformation: kinase-off receptors are more readily methylated than kinase-on, a feature central to adaptational...
Ming-Yuan Su et al.
Nature communications, 8(1), 1516-1516 (2017-11-16)
Peptidoglycan (PG) is a highly cross-linked, protective mesh-like sacculus that surrounds the bacterial cytoplasmic membrane. Expansion of PG is tightly coupled to growth of a bacterial cell and requires hydrolases to cleave the cross-links for insertion of nascent PG material....

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