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A2056
Acetyl coenzyme A trisodium salt
≥93% (HPLC), powder
Synonym(s):
Acetyl-S- CoA, Acetyl CoA
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1 MG
$71.80
5 MG
$123.00
10 MG
$281.00
25 MG
$493.00
100 MG
$1,620.00
$71.80
Available to ship onMay 13, 2025Details
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1 MG
$71.80
5 MG
$123.00
10 MG
$281.00
25 MG
$493.00
100 MG
$1,620.00
About This Item
Empirical Formula (Hill Notation):
C23H35N7O17P3S · 3Na
CAS Number:
Molecular Weight:
875.52
MDL number:
UNSPSC Code:
41106305
PubChem Substance ID:
NACRES:
NA.51
$71.80
Available to ship onMay 13, 2025Details
Recommended Products
Quality Level
assay
≥93% (HPLC)
form
powder
solubility
H2O: 100 mg/mL
storage temp.
−20°C
SMILES string
O[C@H]1[C@](O[C@@H]([C@H]1OP(O)(O)=O)COP(OP(OCC(C)(C)[C@@H](O)C(NCCC(NCCSC(C)=O)=O)=O)(O)=O)(O)=O)([H])N2C3=NC=NC(N)=C3N=C2.[3Na]
InChI
1S/C23H38N7O17P3S.Na/c1-12(31)51-7-6-25-14(32)4-5-26-21(35)18(34)23(2,3)9-44-50(41,42)47-49(39,40)43-8-13-17(46-48(36,37)38)16(33)22(45-13)30-11-29-15-19(24)27-10-28-20(15)30;/h10-11,13,16-18,22,33-34H,4-9H2,1-3H3,(H,25,32)(H,26,35)(H,39,40)(H,41,42)(H2,24,27,28)(H2,36,37,38);/q;+1/p-1/t13-,16-,17-,18?,22-;/m1./s1
InChI key
HNLIOWFIXSPFEC-WLYMNMRISA-M
Gene Information
human ... CHAT(1103) , HAT1(8520) , KAT2A(2648) , KAT2B(8850) , KAT5(10524)
mouse ... HAT1(107435) , KAT2A(14534) , KAT2B(18519) , KAT5(81601)
rat ... HAT1(296501) , KAT2A(303539) , KAT2B(301164) , KAT5(192218)
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Related Categories
Application
Acetyl-CoA is an essential cofactor and carrier of acyl groups in enzymatic acetyl transfer reactions. Acetyl CoA is formed either by the oxidative decarboxylation of pyruvate in mitochondria, by the oxidation of long-chain fatty acids, or by the oxidative degradation of certain amino acids. Acetyl-CoA is the starting compound for the citric acid cycle (Krebs cycle). Acetyl CoA is also a key precursor in lipid biosynthesis, and the source of all fatty acid carbons. Acetyl-CoA positively regulates the activity pyruvate carboxylase. Acetyl CoA is a precursor of the neurotransmitter acetylcholine. Histone acetylases (HAT) use Acetyl-CoA as the donor for the acetyl group use in the post-translational acetylation reactions of histone and non-histone proteins.
An essential cofactor in enzymatic acetyl transfer reactions.
Biochem/physiol Actions
Acetyl-CoA is an essential cofactor and carrier of acyl groups in enzymatic acetyl transfer reactions.
Acetyl-CoA is an essential cofactor and carrier of acyl groups in enzymatic acetyl transfer reactions. It is formed either by the oxidative decarboxylation of pyruvate in mitochondria, by the oxidation of long-chain fatty acids, or by the oxidative degradation of certain amino acids. Acetyl-CoA is the starting compound for the citric acid cycle (Kreb′s cycle). It is also a key precursor in lipid biosynthesis, and the source of all fatty acid carbons. Acetyl-CoA positively regulates the activity pyruvate carboxylase. It is a precursor of the neurotransmitter acetylcholine. Histone acetylases (HAT) use Acetyl-CoA as the donor for the acetyl group use in the post-translational acetylation reactions of histone and non-histone proteins.
Preparation Note
Prepared enzymatically
Other Notes
For more more technical information and a complete list of Coenzyme A deriviatives visit the Acyl Transfer Reagents Resource.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type N95 (US)
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The distinct biochemical function of endoplasmic reticulum (ER) protein Calreticulin (CR) catalyzing the transfer of acyl group from acyloxycoumarin to a receptor protein was termed calreticulin transacylase (CRTAase). The present study, unlike the previous reports of others utilizing CR-deficient cells
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Lysine (K) acetylation refers to transfer of the acetyl moiety from acetyl-CoA to the ε-amino group of a lysine residue. This is posttranslational and reversible, with its level dynamically maintained by lysine acetyltransferases (KATs) and deacetylases (KDACs). Traditionally, eukaryotic KDACs
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Protocols
To measure chloramphenicol acetyltransferase activity, this procedure uses DTNB and coenzyme A. The reaction of DTNB with the –SH group on CoA results in a colorimetric increase at 412 nm.
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For Product No. A2056, Acetyl Coeznyme A, why is the formula weight listed on the website and the formula weight listed on the label different?
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The difference in the formula weights reported for Product No. A2056, Acetyl Coenzyme A, on the website versus the label is due to the sodium and water content of the product which may vary from lot to lot. The formula weight of the free base is reported on the website, however on the label, variations in sodium and water content will reflect differences in formula weights reported on the label for a specific lot of product.
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What is the formula weight for the Product No. A2056, Acetyl Coenzyme A?
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The formula weight for the Product No. A2056, Acetyl Coenzyme A, as reported on the website is for the free base with a weight of 809.57 daltons.
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What is the solution stability for the A2056, Acetyl Coenzyme A?
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The solution stability is reported as followed: A solution of the product can be stored in neutral buffer or below (pH 3-7) for no longer than two weeks at -20°C when divided into aliquots. This is recommended for keeping the solution stable. It would be better to prepare fresh solutions and use soon after.
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