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A3159

Sigma-Aldrich

Adenine hemisulfate salt

powder, BioReagent, suitable for cell culture

Synonym(s):
6-Aminopurine hemisulfate salt, Adenine sulfate salt
Linear Formula:
C5H5N5 · 1/2H2SO4
CAS Number:
Molecular Weight:
184.17
Beilstein:
3820263
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.75

Quality Level

biological source

synthetic (organic)

product line

BioReagent

assay

≥99%

form

powder

technique(s)

cell culture | mammalian: suitable

solubility

0.5 M HCl: 10 mg/mL

SMILES string

OS(O)(=O)=O.Nc1ncnc2[nH]cnc12.Nc3ncnc4[nH]cnc34

InChI

1S/2C5H5N5.H2O4S/c2*6-4-3-5(9-1-7-3)10-2-8-4;1-5(2,3)4/h2*1-2H,(H3,6,7,8,9,10);(H2,1,2,3,4)

InChI key

LQXHSCOPYJCOMD-UHFFFAOYSA-N

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General description

Adenine is a component of DNA, RNA, cofactors nicotinamide adenine dinucleotide (NAD). It is also part of flavin adenine dinucleotide (FAD) and signaling molecules cyclic adenosine monophosphate(cAMP).

Application

Adenine hemisulfate salt has been used:
  • as component of auxotrophy selection reagent for yeast culture
  • as essential nutrient to improve yeast transformation efficiency
  • as a component of synthetic complete (SC) medium for yeast culture

Packaging

5, 25, 100, 500 g in poly bottle

Pictograms

Skull and crossbones

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2

Storage Class Code

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

Effect of preorganization on the affinity of synthetic DNA binding motifs for nucleotide ligands
Vollmer S and Richert C
Organic & Biomolecular Chemistry, 13(20), 5734-5742 (2015)
Base-resolution stratification of cancer mutations using functional variomics
Yi S, et al.
Nature Protocols, 12(11), 2323-2323 (2017)
Mating based split-ubiquitin assay for detection of protein interactions
Horaruang W and Zhang B
Bio-protocol, 7, e2258-e2258 (2017)
Nutrient supplements boost yeast transformation efficiency.
Yu SC, et al.
Scientific Reports, 6, 35738-35738 (2016)
Mengfei Yao et al.
Cell death & disease, 11(8), 638-638 (2020-08-18)
The development of prostate cancer (PCa) from androgen-deprivation therapy (ADT) sensitive to castration resistant (CRPC) seriously impacts life quality and survival of PCa patients. Emerging evidence shows that long noncoding RNAs (lncRNAs) play vital roles in cancer initiation and progression.

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