All Photos(5)

A3159

Sigma-Aldrich

Adenine hemisulfate salt

powder, BioReagent, suitable for cell culture

Synonym(s):
6-Aminopurine hemisulfate salt, Adenine sulfate salt
Linear Formula:
C5H5N5 · 1/2H2SO4
CAS Number:
Molecular Weight:
184.17
Beilstein:
3820263
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.75

Quality Level

biological source

synthetic (organic)

product line

BioReagent

assay

≥99%

form

powder

application(s)

cell culture | mammalian: suitable

solubility

0.5 M HCl: 10 mg/mL

SMILES string

OS(O)(=O)=O.Nc1ncnc2[nH]cnc12.Nc3ncnc4[nH]cnc34

InChI

1S/2C5H5N5.H2O4S/c2*6-4-3-5(9-1-7-3)10-2-8-4;1-5(2,3)4/h2*1-2H,(H3,6,7,8,9,10);(H2,1,2,3,4)

InChI key

LQXHSCOPYJCOMD-UHFFFAOYSA-N

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General description

Adenine is a component of DNA, RNA, cofactors nicotinamide adenine dinucleotide (NAD). It is also part of flavin adenine dinucleotide (FAD) and signaling molecules cyclic adenosine monophosphate(cAMP).

Application

Adenine hemisulfate salt has been used:
  • as component of auxotrophy selection reagent for yeast culture
  • as essential nutrient to improve yeast transformation efficiency
  • as a component of synthetic complete (SC) medium for yeast culture

Packaging

5, 25, 100, 500 g in poly bottle

Pictograms

Skull and crossbones

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2

Storage Class Code

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

Mating based split-ubiquitin assay for detection of protein interactions
Horaruang W and Zhang B
Bio-protocol, 7, e2258-e2258 (2017)
Effect of preorganization on the affinity of synthetic DNA binding motifs for nucleotide ligands
Vollmer S and Richert C
Organic & Biomolecular Chemistry, 13(20), 5734-5742 (2015)
Base-resolution stratification of cancer mutations using functional variomics
Yi S, et al.
Nature Protocols, 12(11), 2323-2323 (2017)
Nutrient supplements boost yeast transformation efficiency.
Yu SC, et al.
Scientific Reports, 6, 35738-35738 (2016)
Abigail R Lambert et al.
Structure (London, England : 1993), 28(7), 760-775 (2020-05-04)
The redesign of a macromolecular binding interface and corresponding alteration of recognition specificity is a challenging endeavor that remains recalcitrant to computational approaches. This is particularly true for the redesign of DNA binding specificity, which is highly dependent upon bending

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