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A3286

Sigma-Aldrich

N-Acetyl-D-glucosamine

suitable for cell culture, BioReagent

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Synonym(s):
2-Acetamido-2-deoxy-D-glucose, D-GlcNAc
Empirical Formula (Hill Notation):
C8H15NO6
CAS Number:
Molecular Weight:
221.21
Beilstein:
1727589
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.75

product line

BioReagent

Assay

≥95% (HPLC)

form

powder

technique(s)

cell culture | mammalian: suitable

mp

211 °C (dec.) (lit.)

storage temp.

−20°C

SMILES string

CC(=O)N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O

InChI

1S/C8H15NO6/c1-3(11)9-5-7(13)6(12)4(2-10)15-8(5)14/h4-8,10,12-14H,2H2,1H3,(H,9,11)/t4-,5-,6-,7-,8?/m1/s1

InChI key

OVRNDRQMDRJTHS-RTRLPJTCSA-N

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This Item
A4106A8625PHR1432
N-Acetyl-D-glucosamine suitable for cell culture, BioReagent

Sigma-Aldrich

A3286

N-Acetyl-D-glucosamine

N-Acetyl-D-glucosamine ≥95% (HPLC)

Sigma-Aldrich

A4106

N-Acetyl-D-glucosamine

N-Acetyl-D-glucosamine ≥99%

Sigma-Aldrich

A8625

N-Acetyl-D-glucosamine

N-Acetylglucosamine Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1432

N-Acetylglucosamine

assay

≥95% (HPLC)

assay

≥95% (HPLC)

assay

≥99%

assay

-

form

powder

form

powder

form

powder

form

-

technique(s)

cell culture | mammalian: suitable

technique(s)

-

technique(s)

HPLC: suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

mp

211 °C (dec.) (lit.)

mp

211 °C (dec.) (lit.)

mp

211 °C (dec.) (lit.)

mp

211 °C (dec.) (lit.)

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-30°C

General description

N-Acetylglucosamine (GlcNAc), a derivative of glucose is a monosaccharide. It is a white powder and is mildly sweet. It melts at 221°C. GlcNAc is 25% soluble in water. It is present in bromelain, ricin agglutinin and abrus agglutinin, in plants. In humans, it is present in tissue plasminogen activator, growth factors and hormones.

Application

N-Acetyl-D-glucosamine addition has been used:
  • as a substrate to develop dot-blots
  • as a substrate to reveal alkaline phosphatase in the immunohistochemical analysis
  • to detect specific immune complexes in western blot analysis

Biochem/physiol Actions

N-Acetylglucosamine (GlcNAc) oligomer may have the ability to initiate factors for canine polymorphonuclear cells (PMN) in vivo. It possesses wound healing and chemotactic activity. GlcNAc and its derivatives are usually employed in preparing dietary supplements and also used in therapeutic development.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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T1503
Product Number
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25G
Pack Size/Quantity

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705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

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Effect of N-acetyl-d-glucosamine and d-glucosamine oligomers on canine polymorphonuclear cells in vitro
Usami Y, et al.
Carbohydrate Polymers, 36(2-3), 137-141 (1998)
Glycoprofiling effects of media additives on IgG produced by CHO cells in fed-batch bioreactors
Kildegaard H F, et al.
Biotechnology and Bioengineering, 113(2), 359-366 (2016)
Glucose metabolism and hexosamine pathway regulate oncogene-induced senescence
Gitenay D, et al.
Cell Death & Disease, 5(2), e1089-e1089 (2014)
Cumulus expansion, nuclear maturation and connexin 43, cyclooxygenase-2 and FSH receptor mRNA expression in equine cumulus-oocyte complexes cultured in vitro in the presence of FSH and precursors for hyaluronic acid synthesis
Dell'Aquila M E, et al.
Reproductive Biology and Endocrinology, 2(1), 44-44 (2004)
Bingwu Yu et al.
Journal of magnetic resonance (San Diego, Calif. : 1997), 228, 159-165 (2013-01-09)
Strong (1)H-(1)H coupling can significantly reduce the accuracy of (1)J(CH) measured from frequency differences in coupled HSQC spectra. Although accurate (1)J(CH) values can be extracted from spectral simulation, it would be more convenient if the same accurate (1)J(CH) values can

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