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A4562

Sigma-Aldrich

5-(N,N-Dimethyl)amiloride hydrochloride

Synonym(s):
3-Amino-N-(aminoiminoethyl)-5-(dimethylamino)-6-chloropyrazinecarboxamide hydrochloride, DMA
Empirical Formula (Hill Notation):
C8H12ClN7O · HCl
CAS Number:
Molecular Weight:
294.14
MDL number:
PubChem Substance ID:
NACRES:
NA.77

form

powder

Quality Level

storage temp.

2-8°C

SMILES string

Cl.CN(C)c1nc(N)c(nc1Cl)C(=O)\N=C(\N)N

InChI

1S/C8H12ClN7O.ClH/c1-16(2)6-4(9)13-3(5(10)14-6)7(17)15-8(11)12;/h1-2H3,(H2,10,14)(H4,11,12,15,17);1H

InChI key

IIUPTHVVXMBJMQ-UHFFFAOYSA-N

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Application

5-(N,N-Dimethyl)amiloride hydrochloride is a selective blocker of Na2/H+ antiport. 5-(N,N-Dimethyl)amiloride hydrochloride has been investigated for its ability to reduce inflammatory pain.

Packaging

25 mg in poly bottle
100 mg in glass bottle

Biochem/physiol Actions

Selective blocker of Na+/H+ antiport; IC50 = 6.9 μM.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

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Certificate of Origin

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Product Information Sheet

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