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A5285

Sigma-Aldrich

Adenosine 5′-diphosphate monopotassium salt dihydrate

bacterial, ≥95%, powder

Synonym(s):

Adenosine 5′-Diphosphate Potassium Salt, ADP

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100 MG
$25.84
1 G
$106.00
5 X 1 G
$519.00

About This Item

Empirical Formula (Hill Notation):
C10H14KN5O10P2 · 2H2O
CAS Number:
Molecular Weight:
501.32
MDL number:
UNSPSC Code:
41106305
eCl@ss:
32160414
PubChem Substance ID:
NACRES:
NA.77

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$25.84

List Price$27.20
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In StockDetails


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biological source

bacterial

Quality Level

assay

≥95%

form

powder

storage temp.

−20°C

SMILES string

[O-]P(OP(OC[C@H]([C@@H](O)[C@H]1O)O[C@H]1N2C3=C(N=C2)C(N)=NC=N3)(O)=O)(O)=O.[K+]

InChI

1S/C10H15N5O10P2.K/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(24-10)1-23-27(21,22)25-26(18,19)20;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H2,11,12,13)(H2,18,19,20);/q;+1/p-1/t4-,6-,7-,10-;/m1./s1

InChI key

ZNCWUOPIJTUALR-MCDZGGTQSA-M

Gene Information

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This Item
A2754A6885117105
form

powder

form

powder

form

powder

form

solid

assay

≥95%

assay

≥95% (HPLC)

assay

≥98.0% (HPLC)

assay

≥98% dry basis (enzymatic)

Quality Level

200

Quality Level

300

Quality Level

200

Quality Level

100

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-8°C

biological source

bacterial

biological source

bacterial

biological source

-

biological source

-

Gene Information

human ... HSP90AA1(3320), P2RY1(5028)

Gene Information

human ... HSP90AA1(3320), P2RY1(5028)

Gene Information

-

Gene Information

-

General description

Adenosine diphosphate (ADP) is a crucial component for energy flow in living organisms. Its structure consists of a sugar backbone connected to adenine and two phosphate groups attached to the fifth carbon atom of the ribose sugar. ADP serves a precursor for ATP biosynthesis.[1] ADP acts as a weak platelet agonist, specifically targeting the P2Y receptor. However, ADP plays a vital role in platelet function by enhancing the effects of other platelet agonists and promoting the stability of platelet aggregates when released from platelet dense granules.[2]

Application

Adenosine 5′-diphosphate has been used to study the release, neuronal effects, and removal of extracellular β-nicotinamide adenine dinucleotide (β-NAD+) in the rat brain. Adenosine 5′-diphosphate has also been used to compare prasugrel versus clopidogrel antiplatelet therapy after acute coronary syndrome.
Adenosine 5′-diphosphate monopotassium salt dihydrate (ADP) has been used:
  • in titration to determine complex I-supported respiration in permeabilized muscle fibers[3]
  • in titrations to determine ADP-stimulated respiratory kinetics[4]
  • in the preparation of ADP solution for measuring mitochondrial respiration[5]

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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