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A5602

Sigma-Aldrich

AMD3100 octahydrochloride hydrate

≥97% (NMR), solid

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Synonym(s):
1,1′-[1,4-Phenylenebis(methylene)]bis-1,4,8,11-tetraazacyclotetradecane octahydrochloride, JM3100, Plerixafor, SID791
Empirical Formula (Hill Notation):
C28H54N8 · 8HCl · xH2O
CAS Number:
Molecular Weight:
794.47 (anhydrous basis)
PubChem Substance ID:
NACRES:
NA.77

Quality Level

assay

≥97% (NMR)

form

solid

storage condition

desiccated

solubility

H2O: ≥10 mg/mL, clear

originator

Sanofi Aventis

storage temp.

−20°C

SMILES string

Cl[H].Cl[H].Cl[H].Cl[H].Cl[H].Cl[H].Cl[H].Cl[H].[H]O[H].C1CNCCNCCCN(CCNC1)Cc2ccc(CN3CCCNCCNCCCNCC3)cc2

InChI

1S/C28H54N8.8ClH.H2O/c1-9-29-15-17-31-13-3-21-35(23-19-33-11-1)25-27-5-7-28(8-6-27)26-36-22-4-14-32-18-16-30-10-2-12-34-20-24-36;;;;;;;;;/h5-8,29-34H,1-4,9-26H2;8*1H;1H2

InChI key

GKFHDCZYJHUPEN-UHFFFAOYSA-N

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1 of 4

This Item
239820239825T1443
vibrant-m

A5602

AMD3100 octahydrochloride hydrate

vibrant-m

239820

CXCR4 Antagonist I, AMD3100

vibrant-m

239825

AMD3100

vibrant-m

T1443

TCPOBOP

assay

≥97% (NMR)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

form

solid

form

solid

form

liquid

form

solid

storage condition

desiccated

storage condition

OK to freeze, desiccated (hygroscopic), protect from light

storage condition

OK to freeze, avoid repeated freeze/thaw cycles, protect from light

storage condition

-

originator

Sanofi Aventis

originator

-

originator

-

originator

-

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

−70°C

storage temp.

2-8°C

Application

AMD3100 is a highly specific chemokine receptor CXCR4 antagonist. AMD3100 has been used in a study to determine the blockade of CXCR4 in oral squamous cell carcinoma and inhibition of lymph node metastases.

Biochem/physiol Actions

AMD3100 is a highly specific chemokine receptor CXCR4 antagonist.

Features and Benefits

This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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