A6390

β-D-Allose

rare aldohexose sugar

• Synonym(s): β-D-Allopyranose
• Empirical Formula (Hill Notation): C₆H₁₂O₆
• CAS Number: 7283-09-2
• Molecular Weight: 180.16
• MDL number: MFCD00063268
• PubChem Substance ID: 24891083

Properties

• Quality Level: 200
• assay: ≥98% (HPLC); ≥98% (TLC)
• form: powder
• optical activity: [α]/D 12.00 to 16.00 °, c = 45.00-55.00 mg/mL in water
• technique(s): HPLC: suitable; thin layer chromatography (TLC): suitable
• SMILES string: OC[C@H]1O[C@@H](O)[C@H](O)[C@H](O)[C@@H]1O
• InChI: 1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4-,5-,6-/m1/s1
• InChI key: WQZGKKKJIJFFOK-QZABAPFNSA-N

Description

Application

β-D-Allose (β-D-Allose), a rare sugar member of the aldohexose family and a C3 epimer of glucose, is used as an inhibitor of fruiting body formation and sporulation in Myxococcus xanthus.

Packaging

10, 25, 100, 250 mg in glass bottle

1 g in glass bottle

Biochem/physiol Actions

D-Allose is a rare aldohexose sugar that has demonstrated anti-cancer, antitumor, anti-inflammatory, anti-oxidative, antihypertensive, cryoprotective, and immunosuppressant activities. D-Allose upregulates thioredoxin-interacting protein (TXNIP) gene expression and was found to induce G1 cell cycle arrest in hepatocellular carcinoma cells. It inhibited transcriptional activity of the activator protein 1, nuclear factor-κB, and nuclear factor of activated T cells. D-Allose decreases transport of 2-deoxy-D-glucose and 3-O-methyl-D-glucose in V79 Chinese hamster lung fibroblast cells.

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves