Aflatoxin M1

from Aspergillus flavus

Empirical Formula (Hill Notation):
CAS Number:
Molecular Weight:
EC Number:
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PubChem Substance ID:
Pricing and availability is not currently available.

Quality Level

biological source

Aspergillus flavus

storage temp.


SMILES string




InChI key


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General description

Aflatoxins are metabolites of fungus, that are mainly seen in feeds and foods. Aflatoxin M1 is a hydroxylated metabolite of aflatoxin B1. It is liberated in milk, urine and produced in liver after receiving aflatoxin B1.


Aflatoxin M1 has been used as a standard to investigate the incidence and occurrence of aflatoxin M1 (AFM1) in Brazilian milk and infant formula. It has also been used as standard to investigate the incidence and occurrence of aflatoxin M1 (AFM1) in dairy products produced in Brazil.
Aflatoxin M1 is both a hepatotoxic and hepatocarcinogenic mycotoxin that has been shown to cause immunosuppression in animals.

Biochem/physiol Actions

Aflatoxin M1 possesses hepatocarcinogenic properties.


Possibly carcinogenic.

Preparation Note

Aspergillus flavus metabolite.


Skull and crossbonesHealth hazard

Signal Word



UN 3462 6.1 / PGI

WGK Germany


Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis
Certificate of Origin
Handbook of Secondary Fungal Metabolites (2003)
Handbook of Secondary Fungal Metabolites, 545-569 (2003)
Aflatoxin M1 in milk and distribution and stability of aflatoxin M1 during production and storage of yoghurt and cheese
Iha MH, et al.
Food Control, 29(1), 1-6 (2013)
Nathalie Paniel et al.
Sensors (Basel, Switzerland), 10(10), 9439-9448 (2010-01-01)
We have developed an electrochemical immunosensor for the detection of ultratrace amounts of aflatoxin M(1) (AFM(1)) in food products. The sensor was based on a competitive immunoassay using horseradish peroxidase (HRP) as a tag. Magnetic nanoparticles coated with antibody (anti-AFM(1))...
Occurrence of aflatoxin M1 in dairy products in Brazil
Iha MH, et al.
Food Control, 22(12), 1971-1974 (2011)
Cancer research has revealed that the classical model of carcinogenesis, a three step process consisting of initiation, promotion, and progression, is not complete.
Read More
Protocol for LC/MS Analysis of Aflatoxin M1 in Milk on Ascentis® Express HILIC after SPE using Supel™ Tox AflaZea, Quantifying Picogram Concentrations
Read More

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