Z Rakonczay et al.
Journal of neurochemistry, 46(1), 280-287 (1986-01-01)
Seven unique monoclonal antibodies were generated to rat brain acetylcholinesterase. Upon density gradient ultracentrifugation, immunoglobulin complexes with the monomeric enzyme appeared as single peaks of acetylcholinesterase activity with a sedimentation coefficient approximately 3S greater than that of the free enzyme....
Jose R Suarez-Lopez et al.
Pediatrics, 132(6), e1649-e1658 (2013-11-20)
Organophosphate exposures can affect children's neurodevelopment, possibly due to neurotoxicity induced by acetylcholinesterase (AChE) inhibition, and may affect boys more than girls. We tested the hypothesis that lower AChE activity is associated with lower neurobehavioral development among children living in...
Expert opinion on therapeutic patents, 22(8), 871-886 (2012-07-10)
Both acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) are present in the body in large amounts. AChE is an important part of the cholinergic nervous system taking place in the central and peripheral nervous system. AChE is a target of several toxins...
Holmes, C. et al.
The Journal of Neuroscience, 49, 207-207 (1997)
Matthew W Rice et al.
Frontiers in neuroanatomy, 5, 53-53 (2011-09-03)
The striatum is a major component of the basal ganglia and is associated with motor and cognitive functions. Striatal pathologies have been linked to several disorders, including Huntington's, Tourette's syndrome, obsessive-compulsive disorders, and schizophrenia. For the study of these striatal...