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MilliporeSigma

A7469

Sigma-Aldrich

L-Alanine

98.5-101.0%, suitable for cell culture, BioXtra, non-animal source

Synonym(s):

(S)-2-Aminopropionic acid, L-α-Aminopropionic acid

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10 MG
$28.85
25 G
$57.00
100 G
$177.00
1 KG
$991.90

About This Item

Empirical Formula (Hill Notation):
C3H7NO2
CAS Number:
Molecular Weight:
89.09
Beilstein/REAXYS Number:
1720248
EC Number:
MDL number:
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.26

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$28.85

List Price$31.70Save 9%
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In StockDetails


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Product Name

L-Alanine, from non-animal source, meets EP, USP testing specifications, suitable for cell culture, 98.5-101.0%

biological source

non-animal source

Quality Level

agency

meets EP testing specifications
meets USP testing specifications

product line

BioXtra

assay

98.5-101.0%

form

powder

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

color

white

solubility

H2O: 100 mg/mL

application(s)

peptide synthesis
pharmaceutical (small molecule)

SMILES string

C[C@H](N)C(O)=O

InChI

1S/C3H7NO2/c1-2(4)3(5)6/h2H,4H2,1H3,(H,5,6)/t2-/m0/s1

InChI key

QNAYBMKLOCPYGJ-REOHCLBHSA-N

Gene Information

human ... CA1(759), CA2(760)

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1 of 4

This Item
445261250492876
L-Alanine from non-animal source, meets EP, USP testing specifications, suitable for cell culture, 98.5-101.0%

A7469

L-Alanine

L-Alanine certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

44526

L-Alanine

L-Alanine A non-essential amino acid.

1250

L-Alanine

form

powder

form

-

form

solid

form

-

assay

98.5-101.0%

assay

-

assay

≥98% dry basis (titration)

assay

-

technique(s)

cell culture | mammalian: suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

-

technique(s)

-

product line

BioXtra

product line

TraceCERT®

product line

-

product line

-

Quality Level

200

Quality Level

300

Quality Level

100

Quality Level

200

color

white

color

white

color

white

color

-

Application

L-Alanine has been used for tissue culture technique as a media component. It has been used as a media component for the growth of adult mouse keratinocytes.[1][2]

Biochem/physiol Actions

L-Alanine is a nonessential amino acid, which is highly concentrated in muscle.[3] It is a key player in the Glucose-Alanine cycle, which enables the removal of pyruvate and glutamate from muscle to the liver.[4][5] Once in the liver, glucose is regenerated from pyruvate and returned to the muscle while glutamate ultimately participates in the urea cycle to form urea. The Glucose-Alanine cycle aides to conserve ATP in muscle for muscle contraction, while the energy burden of gluconeogenesis is imposed upon the liver.[5][3] Alanine inhibits pyruvate kinase to regulate gluconeogenesis and glycolysis in order to maintain glucose homeostasis during starvation. Alanine prevents hepatic autophagy. Alanine formation is a result of transamination of glutamate and pyruvate.[4][3]

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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