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A7655

Sigma-Aldrich

Atenolol

≥98% (TLC), powder

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Synonym(s):
(±)-4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzeneacetamide, 4-[2′-Hydroxy-3′-(isopropylamino)propoxy]phenylacetamide
Empirical Formula (Hill Notation):
C14H22N2O3
CAS Number:
29122-68-7
Molecular Weight:
266.34
EC Number:
249-451-7
MDL number:
MFCD00057645
PubChem Substance ID:
24277748
NACRES:
NA.77

Quality Level

200

Assay

≥98% (TLC)

form

powder

color

white to off-white

solubility

H2O: 0.3 mg/mL
DMSO: 18 mg/mL
ethanol: 3.4 mg/mL

originator

AstraZeneca

SMILES string

CC(C)NCC(O)COc1ccc(CC(N)=O)cc1

InChI

1S/C14H22N2O3/c1-10(2)16-8-12(17)9-19-13-5-3-11(4-6-13)7-14(15)18/h3-6,10,12,16-17H,7-9H2,1-2H3,(H2,15,18)

InChI key

METKIMKYRPQLGS-UHFFFAOYSA-N

Gene Information

human ... ADRB1(153)
rat ... Adrb1(24925)

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1 of 4

This Item
1044403PHR1909A1340000
Atenolol ≥98% (TLC), powder

Sigma-Aldrich

A7655

Atenolol

Atenolol United States Pharmacopeia (USP) Reference Standard

USP

1044403

Atenolol

Atenolol Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1909

Atenolol

Atenolol European Pharmacopoeia (EP) Reference Standard

A1340000

Atenolol

form

powder

form

-

form

powder

form

-

color

white to off-white

color

-

color

-

color

-

solubility

H2O: 0.3 mg/mL, DMSO: 18 mg/mL, ethanol: 3.4 mg/mL

solubility

-

solubility

-

solubility

-

originator

AstraZeneca

originator

-

originator

-

originator

-

Gene Information

human ... ADRB1(153)
rat ... Adrb1(24925)

Gene Information

human ... ADRB1(153)

Gene Information

human ... ADRB1(153)

Gene Information

human ... ADRB1(153)

Application

Atenolol is a β-adrenergic blocker and used in the management of hypertension. Atenolol has antianginal and antiarrhythmic properties.

Biochem/physiol Actions

Selective β1-adrenoceptor antagonist; antihypertensive; antianginal; antiarrhythmic.

Features and Benefits

This compound is featured on the β-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by AstraZeneca. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Other Notes

Shelf-life of the solid is at least three years.

standard

Product No.
Description
Pricing

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Chromatograms

application for HPLC

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