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A7791

Sigma-Aldrich

N-Acetyl-D-lactosamine

≥98%

All Photos(2)
Synonym(s):
2-Acetamido-2-deoxy-4-O-β-D-galactopyranosyl-D-glucopyranose, β-D-Gal-(1→4)-D-GlcNAc, N-Acetyl-4-O-(β-D-galactopyranosyl)-D-glucosamine, LN
Empirical Formula (Hill Notation):
C14H25NO11
CAS Number:
32181-59-2
Molecular Weight:
383.35
Beilstein:
96808
MDL number:
MFCD00063785
PubChem Substance ID:
24891280
NACRES:
NA.25

Quality Level

100

assay

≥98%

form

powder

optical activity

[α]25/D 27.5 to 32.5 °, c = 0.5% (w/v) in water

application(s)

thin layer chromatography (TLC): suitable

storage temp.

−20°C

SMILES string

CC(=O)N[C@H]1C(O)O[C@H](CO)[C@@H](O[C@@H]2O[C@H](CO)[C@H](O)[C@H](O)[C@H]2O)[C@@H]1O

InChI

1S/C14H25NO11/c1-4(18)15-7-9(20)12(6(3-17)24-13(7)23)26-14-11(22)10(21)8(19)5(2-16)25-14/h5-14,16-17,19-23H,2-3H2,1H3,(H,15,18)/t5-,6-,7-,8+,9-,10+,11-,12-,13?,14+/m1/s1

InChI key

KFEUJDWYNGMDBV-RPHKZZMBSA-N

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Application

N-Acetyl-D-lactosamine is used as a specific lectin target molecule in the identification and differentiation of sugar binding molecules such as the galectins. N-Acetyl-D-lactosamine is used in studies of galactosidase, fucosyltransferase, sialyltransferase, and lectin inhibition.
Useful in studies of galactosidase, fucosyltransferase, sialyltransferase, and lectin inhibition.

Packaging

10 mg in autosample vial

Preparation Note

Synthetic

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

Meghan Rothenberger et al.
Journal of acquired immune deficiency syndromes (1999), 81(3), 355-360 (2019-06-14)
HIV is produced in lymphoid tissues (LT) and stored on the follicular dendritic cell network in LT. When antiretroviral therapy is started, plasma viremia decays in 2 phases; the first within days of starting therapy and the second over weeks....
Moritz Augustin et al.
PLoS computational biology, 13(6), e1005545-e1005545 (2017-06-24)
The spiking activity of single neurons can be well described by a nonlinear integrate-and-fire model that includes somatic adaptation. When exposed to fluctuating inputs sparsely coupled populations of these model neurons exhibit stochastic collective dynamics that can be effectively characterized...
Paulina Sindrewicz et al.
Scientific reports, 9(1), 11851-11851 (2019-08-16)
Galectins are involved in the regulation of divergent physiological and pathological processes and are increasingly recognized to play important roles in a number of diseases. However, a simple and effective way in assessing galectin-ligand interactions is lacking. Our examination of...
Vanessa Dumeaux et al.
PLoS computational biology, 13(9), e1005680-e1005680 (2017-09-29)
Although systemic immunity is critical to the process of tumor rejection, cancer research has largely focused on immune cells in the tumor microenvironment. To understand molecular changes in the patient systemic response (SR) to the presence of BC, we profiled...
Magdalena Osiewicz et al.
Journal of clinical medicine, 8(7) (2019-07-03)
The aim was to determine the occurrence of temporomandibular disorders (TMDs) in patients with Lyme disease (LD), and to estimate the contribution of factors that may identify TMD among LD patients. In seventy-six (N = 76) adult patients with LD...
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