L-Asparagine monohydrate

≥99% (TLC)

(S)-2-Aminosuccinic acid 4-amide, L-Aspartic acid 4-amide, (S)-(+)-2-Aminosuccinamic acid
Linear Formula:
CAS Number:
Molecular Weight:
Beilstein/REAXYS Number:
EC Number:
MDL number:
PubChem Substance ID:

Quality Level

biological source



≥99% (TLC)




cell analysis: suitable
peptide synthesis: suitable


white to off-white


233-235 °C (lit.)

SMILES string




InChI key


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General description

Asparagine biosynthesis is catalyzed by glutamine-dependent asparagine synthetase in mammalian tissues. Elevated levels of free asparagine is observed in plants facing stress in the form of drought or high salt. It is also present in senescing leaves and germinating seeds.


L-Asparagine monohydrate has been used:
  • as a component of Sauton′s and chelated Sauton′s media for mycobacterial growth
  • to test its effect in the induction of Ca2+ flux in rice roots using aequorin luminescence imaging
  • as a component of fermentation medium for the Blakeslea trispora spores


100 g in poly bottle
1 kg in poly bottle

Biochem/physiol Actions

Asparagine has high nitrogen to carbon ratio and is a key regulator for nitrogen storage and transport. Its thermal degradation in the presence of sugars leads to the acrylamide formation in foods. Asparagine serves as an amino acid exchange factor and is essential for amino acid homeostasis. It favors cancer cell proliferation.
L-Asparagine, a proteinogenic amino acid, is used in biomanufacturing cell culture systems for the production of therapeutic recombinant proteins and monoclonal antibodies and in cell culture based research.

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves


NONH for all modes of transport

WGK Germany


Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Asparagine promotes cancer cell proliferation through use as an amino acid exchange factor
Krall AS, et al.
Nature Communications, 7(1), 11457-11457 (2016)
Heterologous expression and functional analysis of rice GLUTAMATE RECEPTOR-LIKE family indicates its role in glutamate triggered calcium flux in rice roots
Ni J, et al.
Rice (New York, N.Y.), 9(1), 9-9 (2016)
Asparagine Synthesis
The Enzymes, 10, 561-580 (1974)
Asparagine in plants
Lea PJ, et al.
The Annals of applied biology, 150(1), 1-26 (2007)
Oxidative stress response and morphological changes of Blakeslea trispora induced by butylated hydroxytoluene during carotene production
Nanou K and Roukas T
Applied Biochemistry and Biotechnology, 160(8), 2415-2423 (2010)

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