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Key Documents

A9126

Sigma-Aldrich

Adenine hemisulfate salt

≥99%

Synonym(s):

6-Aminopurine hemisulfate salt, Adenine sulfate salt

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About This Item

Linear Formula:
C5H5N5 · 1/2H2SO4
CAS Number:
Molecular Weight:
184.17
Beilstein/REAXYS Number:
3820263
EC Number:
MDL number:
UNSPSC Code:
41106305
PubChem Substance ID:
NACRES:
NA.51

biological source

synthetic (organic)

Quality Level

assay

≥99%

form

powder

solubility

0.5 M HCl: 10 mg/mL, clear, colorless

SMILES string

OS(O)(=O)=O.Nc1ncnc2[nH]cnc12.Nc3ncnc4[nH]cnc34

InChI

1S/2C5H5N5.H2O4S/c2*6-4-3-5(9-1-7-3)10-2-8-4;1-5(2,3)4/h2*1-2H,(H3,6,7,8,9,10);(H2,1,2,3,4)

InChI key

LQXHSCOPYJCOMD-UHFFFAOYSA-N

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Application

Adenine hemisulfate salt has been used as a component of:
  • complete supplement mixture (CSM)
  • yeast extract with supplements (YES) medium for culturing S. pombe strain
  • synthetic complete glucose-based yeast media (SC) for S. cerevisiae cultures

Biochem/physiol Actions

Adenine is a purine nucleobase with a wide range of chemical and biochemical roles in vivo and in vitro. It is a regulatory molecule and a component of DNA, RNA, cofactors nicotinamide adenine dinucleotide (NAD), flavin adenine dinucleotide (FAD) and signaling molecules (cAMP).

pictograms

Skull and crossbones

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Certificates of Analysis (COA)

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Methods (San Diego, Calif.), 48(3), 311-319 (2009-03-11)
We describe a detailed and widely applicable method for comprehensive proteomic profiling of the fission yeast Schizosaccharomyces pombe by 2-dimensional high performance liquid chromatography-electrospray ionization-tandem mass spectrometry that demonstrates high sensitivity and robust operation. Steps ranging from the preparation of
Olivia Ballew et al.
Current biology : CB, 29(3), 449-460 (2019-01-29)
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Gut microbiota impacts the host metabolome and affects its health span. How bacterial species in the gut influence age-dependent metabolic alteration has not been elucidated. Here we show in Drosophila melanogaster that allantoin, an end product of purine metabolism, is

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