All Photos(4)

A9126

Sigma-Aldrich

Adenine hemisulfate salt

≥99%

Synonym(s):
6-Aminopurine hemisulfate salt, Adenine sulfate salt
Linear Formula:
C5H5N5 · 1/2H2SO4
CAS Number:
Molecular Weight:
184.17
Beilstein:
3820263
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.51

Quality Level

biological source

synthetic (organic)

assay

≥99%

form

powder

solubility

0.5 M HCl: 10 mg/mL, clear, colorless

SMILES string

OS(O)(=O)=O.Nc1ncnc2[nH]cnc12.Nc3ncnc4[nH]cnc34

InChI

1S/2C5H5N5.H2O4S/c2*6-4-3-5(9-1-7-3)10-2-8-4;1-5(2,3)4/h2*1-2H,(H3,6,7,8,9,10);(H2,1,2,3,4)

InChI key

LQXHSCOPYJCOMD-UHFFFAOYSA-N

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Application

Adenine hemisulfate salt has been used as a component of:
  • complete supplement mixture (CSM)
  • yeast extract with supplements (YES) medium for culturing S. pombe strain
  • synthetic complete glucose-based yeast media (SC) for S. cerevisiae cultures

Packaging

25, 100 g in poly bottle
1 kg in poly bottle

Biochem/physiol Actions

Adenine is a purine nucleobase with a wide range of chemical and biochemical roles in vivo and in vitro. It is a regulatory molecule and a component of DNA, RNA, cofactors nicotinamide adenine dinucleotide (NAD), flavin adenine dinucleotide (FAD) and signaling molecules (cAMP).

Pictograms

Skull and crossbones

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2

Storage Class Code

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

Laurence M Brill et al.
Methods (San Diego, Calif.), 48(3), 311-319 (2009-03-11)
We describe a detailed and widely applicable method for comprehensive proteomic profiling of the fission yeast Schizosaccharomyces pombe by 2-dimensional high performance liquid chromatography-electrospray ionization-tandem mass spectrometry that demonstrates high sensitivity and robust operation. Steps ranging from the preparation of
Pin-Chao Liao et al.
Methods in cell biology, 155, 295-319 (2020-03-19)
The redox state of mitochondria is determined by the levels of reducing and oxidizing species in the organelle, which reflects mitochondrial metabolic activity and overall fitness. Mitochondria are also the primary endogenous source of reactive oxygen species (ROS). This chapter
Burak Yazgan et al.
Experimental biology and medicine (Maywood, N.J.), 246(17), 1917-1927 (2021-05-25)
Chronic kidney disease is a major global public health problem. The peptide hormones adropin and spexin modulate many physiological functions such as energy balance and glucose, lipid and protein metabolism. However, it is unclear whether these peptides may exert effects
Dual-probe RNA FRET-FISH in Yeast
Wadsworth GM, et al.
Bio-protocol, 8(11) (2018)
Toshitaka Yamauchi et al.
iScience, 101477-101477 (2020-09-12)
Gut microbiota impacts the host metabolome and affects its health span. How bacterial species in the gut influence age-dependent metabolic alteration has not been elucidated. Here we show in Drosophila melanogaster that allantoin, an end product of purine metabolism, is

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