• A9202
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Angiotensin Fragment 1-7 acetate salt hydrate

≥90% (HPLC), powder

Empirical Formula (Hill Notation):
C41H62N12O11 · xC2H4O2 · yH2O
Molecular Weight:
899.00 (anhydrous free base basis)
MDL number:
PubChem Substance ID:

Quality Level


≥90% (HPLC)



UniProt accession no.

storage temp.


SMILES string




InChI key


Gene Information

human ... AGT(183)

Amino Acid Sequence



Angiotensin Fragment 1-7 acetate salt hydrate has been used:
  • to evaluate its effects on a rat model of ventilator-induced diaphragmatic dysfunction (VIDD) with neuromuscular blocking agent infusion
  • to unilaterally inject into the lateral preoptic area (LPA) to study its effects on intravesical pressure, arterial pressure, heart rate, and renal conductance in the female rats
  • to study its association with influenza A virus (IAV) infection

Biochem/physiol Actions

Angiotensin fragment 1-7 is a biologically active heptapeptide of the renin-angiotensin system (RAS). It is associated with anti-inflammatory and anti-fibrotic effects in many inflammatory diseases such as asthma, dyslipidemia, renal injury, arthritis, and lung fibrosis. Angiotensin fragment 1-7 acts as a pro-resolving mediator and induces resolution of inflammation via Mas receptor (MasR). It is responsible for relaxation in several vascular beds. Angiotensin fragment 1-7 has a dual action of an angiotensin II type 1 (AT1) receptor agonist and antagonist depending on the presence of angiotensin II. It also serves as a substrate for angiotensin-converting enzyme (ACE). Sometimes, angiotensin fragment 1-7 prevents ACE activity leading to decreased angiotensin II generation and improved bradykinin-induced vasodilatation.

Other Notes

Lyophilized from 0.5% acetic acid

Storage Class Code

11 - Combustible Solids



Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

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Certificate of Origin

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