Effects of different states of sheep fetal fibroblasts as donor cells on the early development in vitro of reconstructed sheep embryos
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The Journal of nutritional biochemistry, 59, 37-48 (2018-07-01)
Lipotoxicity is associated with a high level of fatty acid accumulation in pancreatic β-cells. An overload of free fatty acids contributes to pancreatic β-cell apoptosis and dysfunction. Insulin secretion involves sequential ionic events upon glucose stimulation. ATP sensitive potassium (KATP)...
Yi Fan et al.
SLAS discovery : advancing life sciences R & D, 23(7), 742-750 (2018-06-07)
Enhancing antitumor activities of the human immune system is a clinically proven approach with the advent of monoclonal antibodies recognizing programmed cell death protein-1 (PD1) receptors on immune cell surfaces. Historically, using flow cytometry as a means to assess next-generation...
Down-regulation of the mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase gene by insulin: the role of the forkhead transcription factor FKHRL1
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The Biochemical Journal, 366(1), 289-297 (2002)
Glucagon receptor antagonism induces increased cholesterol absorption
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Journal of Lipid Research, 56(11), 2183-2195 (2015)